論文リスト(2009-現在)
2017
  1. Uemura, T., Suzuki, T., Saiki, R., Dohmae, N., Ito, S., Takahashi, H., Toida, T., Kashiwagi, K., Igarashi, K.: Activation of MMP-9 activity by acrolein in saliva from patients with primary Sjögren's syndrome and its mechanism.Int. J. Biochem. Cell Biol. in press
  2. Yamada, T., Kerever, A., Yoshimura, Y., Suzuki, Y., Nonaka, R., Higashi, K., Toida, T., Mercier, F., Arikawa-Hirasawa, E.: Heparan Sulfate Alterations in Extracellular Matrix Structures and FGF-2 Signaling Impairment in the Aged Neurogenic Niche. J. Neurochem. in press
2016
  1. Tamai, N., Akase, T., Minematsu, T., Higashi, K., Toida, T., Igarashi, K., Sanada, H.: Association between components of exudates and periwound moisture-associated dermatitis in breast cancer patients with malignant fungating wounds. Biol. Res. Nurs. 18, 199-206 (2016)
  2. Nakamura, M., Uemura, T., Saiki, R., Sakamoto, A., Park, H., Nishimura, K., Terui, Y., Toida, T., Kashiwagi, K., Igarashi, K.: Toxic acrolein production due to Ca(2+) influx by the NMDA receptor during stroke. Atherosclerosis 244, 131-137 (2016)
  3. Uemura, T., Watanabe, K., Ishibashi, M., Saiki, R., Kuni, K., Nishimura, K., Toida, T., Kashiwagi, K., Igarashi, K.: Aggravation of brain infarction through an increase in acrolein production and a decrease in glutathione with aging. Biochem. Biophys. Res. Commun. 473, 630-635 (2016)
  4. Ge, D., Higashi, K., Ito, D., Nagano, K., Ishikawa, R., Terui, Y., Higashi, K., Moribe, K., Linhardt, R.J., Toida, T.: Poly-ion Complex of Chondroitin Sulfate and Spermine and Its Effect on Oral Chondroitin Sulfate Bioavailability. Chem. Pharm. Bull. 64, 390-398 (2016)
  5. Higashi, K., Igarashi, K., Toida, T.: Recent Progress in Analytical Methods for Determination of Urinary 3-Hydroxypropylmercapturic Acid, a Major Metabolite of Acrolein. Biol. Pharm. Bull. 39, 915-919 (2016)
  6. Sugiyama, S., Ishikawa, S., Tomitori, H., Niiyama, M., Hirose, M., Miyazaki, Y., Higashi, K., Murata, M., Adachi, H., Takano, K., Murakami, S., Inoue, T., Mori, Y., Kashiwagi, K., Igarashi, K., Matsumura, H.: Molecular mechanism underlying promiscuous polyamine recognition by spermidine acetyltransferase. Int. J. Biochem. Cell Biol. 76, 87-97 (2016)
  7. Imamura, M., Higashi, K., Yamaguchi, K., Asakura, K., Furihata, T., Terui, Y., Satake, T., Maegawa, J., Yasumura, K., Ibuki, A., Akase, T., Nishimura, K., Kashiwagi, K., Linhardt, R.J., Igarashi, K., Toida, T.: Polyamines release the let-7b-mediated suppression of initiation codon recognition during the protein synthesis of EXT2. Sci. Rep. 6, 33549 (2016)
  8. Higashi, K., Takeda, K., Mukuno, A., Okamoto, Y., Masuko, S., Linhardt, R.J., Toida, T.: Identification of keratan sulfate disaccharide at C-3 position of glucuronate of chondroitin sulfate from Mactra chinensis. Biochem. J. 473, 4145-4158 (2016)
  9. Sugiyama, Y., Nakamura, A., Matsumoto, M., Kanbe, A., Sakanaka, M., Higashi, K., Igarashi, K., Katayama, T., Suzuki, H., Kurihara, S.: A novel putrescine exporter SapBCDF of Escherichia coli. J. Biol. Chem, 291, 26343-26351 (2016)
2015
  1. Terui, Y., Sakamoto, A., Yoshida, T., Kasahara, T., Tomitori, H., Higashi, K., Igarashi, K., Kashiwagi, K.: Polyamine stimulation of eEF1A synthesis based on the unusual position of a complementary sequence to 18S rRNA in eEF1A mRNA. Amino Acids 47, 345-356 (2015)
  2. Yoshida, M., Higashi, K., Kuni, K., Mizoi, M., Saiki, R., Nakamura, M., Waragai, M., Uemura, K., Toida, T., Kashiwagi, K., Igarashi, K.: Distinguishing mild cognitive impairment from Alzheimer's disease with acrolein metabolites and creatinine in urine. Clin. Chim. Acta 441, 115-121 (2015)
  3. Higashi, K., Takeuchi, Y., Mukuno, A., Tomitori, H., Miya, M., Linhardt, R.J., Toida, T.: Composition of Glycosaminoglycans in Elasmobranchs including Several Deep-Sea Sharks: Identification of Chondroitin/Dermatan Sulfate from the Dried Fins of Isurus oxyrinchus and Prionace glauca. PLoS One 10, e0120860 (2015)
  4. Suabjakyong, P., Saiki, R., Van Griensven, L.J., Higashi, K., Nishimura, K., Igarashi, K., Toida, T.: Polyphenol Extract from Phellinus igniarius Protects against Acrolein Toxicity In Vitro and Provides Protection in a Mouse Stroke Model. PLoS One 10, e0122733 (2015)
  5. Akiyama, H., Matsuoka, H., Okuyama, T., Higashi, K., Toida, T., Komatsu, H., Sugita-Konishi, Y., Kobori, S., Kodama, Y., Yoshida, M., Endou, H.: The acute encephalopathy induced by intake of sugihiratake mushroom in the patients with renal damage might be associated with the intoxication of cyanide and thiocyanate. Food Safety 3, 16-29 (2015)
  6. Hirose, T., Saiki, R., Yoshizawa, Y., Imamura, M., Higashi, K., Ishii, I., TToida, T., Williams, K., Kashiwagi, K., Igarashi, K.: Spermidine and Ca2+, but not Na+, can permeate NMDA receptors consisting of GluN1 and GluN2A or GluN2B in the presence of Mg2+. Biochem. Biophys. Res. Commun. 463, 1190-1195 (2015)
  7. Suabjakyong, P., Nishimura, K., Toida, T., Van Griensven, L.J.: Structural characterization and immunomodulatory effects of polysaccharides from Phellinus linteus and Phellinus igniarius on the IL-6/IL-10 cytokine balance of the mouse macrophage cell lines (RAW 264.7). Food Funct. 6, 2834-2844 (2015)
  8. Higashi, K., Okamoto, Y., Mukuno, A., Wakai, J., Hosoyama, S., Linhardt, R.J. Toida, T.: Functional chondroitin sulfate from Enteroctopus dofleini containing a 3-O-sulfo glucuronic acid residue. Carbohydr. Polym. 134, 557-565 (2015)
  9. Hirose, T., Saiki, R., Uemura, T., Suzuki, T., Dohmae, N., Ito, S., Takahashi, H., Ishii, I., Toida, T., Kashiwagi, K., Igarashi, K.: Increase in acrolein-conjugated immunoglobulins in saliva from patients with primary Sjögren's syndrome. Clin. Chim. Acta 450, 184-189 (2015)
2014
  1. Terui, Y., Saroj, S.D., Sakamoto, A., Yoshida, T., Higashi, K., Kurihara, S., Suzuki, H., Toida, T., Kashiwagi, K., Igarashi, K.: Properties of putrescine uptake by PotFGHI and PuuP and their physiological significance in Escherichia coli. Amino Acids 46, 661-70 (2014)
  2. Li, G., Cai, C., Li, L., Fu, L., Chang, Y., Zhang, F., Toida, T., Xue, C., Linhardt, R.J.: Method to detect contaminants in heparin using radical depolymerization and liquid chromatography-mass spectrometry. Anal Chem. 86, 326-30 (2014)
  3. Weisel, F.C., Kloepping, C., Pichl, A., Sydykov, A., Kojonazarov, B., Wilhelm, J., Roth, M., Ridge, K.M., Igarashi, K., Nishimura, K., Maison, W., Wackendorff, C., Klepetko, W., Schermuly, R.T., Ghofrani, H.A., Grimminger, F., Seeger, W., Weissmann, N., and Kwapiszewska, G.: Impact of S-adenosylmethionine decarboxylase 1 in pulmonary vascular remodeling. Circulation 129, 1510-1523 (2014)
  4. Higashi, K., Imamura, M., Fudo, S., Uemura, T., Saiki, R., Hoshino, T., Toida, T., Kashiwagi, K., Igarashi, K.: Identification of functional amino acid residues involved in polyamine and agmatine transport by human organic cation transporter 2. PLoS One 9, e102234 (2014)
  5. Higashi, K., Okamoto, Y., Mano, T., Wada, T., Toida, T.: 16. A simple HPLC method for identification of the origin of chondroitin sulfate in health foods. Jpn. J. Food Chem. 21, 187-194 (2014)
2013
  1. Igarashi, N., Takeguchi, A., Sakai, S., Akiyama, H., Higashi, K., Toida, T.: Effect of molecular sizes of chondroitin sulfate on iteraction with L-Selectin. Int. J. Carbohydr. Chem. 2013 Article ID 856142, 9 pages (2013)
  2. Niiyama. M., Sugiyama, S., Hirose, M., Ishikawa, S., Tomitori, H., Higashi, K., Yamashita, T., Adachi, H., Takano, K., Murakami, S., Murata, M., Inoue, T., Mori, Y., Kashiwagi, K., Matsumura, H., and Igarashi K.: Expression, purification, crystallization and preliminary crystallographic analysis of spermidine acetyltransferase from Escherichia coli. Acta. Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 69, 884-887 (2013)
  3. Hayashi, Y., Sugiyama, H., Suganami, A., Higashi, K., Kashiwagi, K., Igarashi, K., Kawauchi, S., Tamura, Y.: Prediction of the interaction between spermidine and the G-G mismatch containing acceptor stem in tRNA(Ile): molecular modeling, density functional theory, and molecular dynamics study. Biochem. Biophys. Res. Commun. 441, 999-1004 (2013)
  4. Saiki, R., Hayashi, D., Ikuo, Y., Nishimura, K., Ishii, I., Kobayashi, K., Chiba, K., Toida, T., Kashiwagi, K., and Igarashi, K.: Acrolein stimulation of the synthesis of IL-6 and CRP in thrombosis model mice and cultured cells. J. Neurochem. 127, 652-659 (2013)
  5. Yamashita, T., Nishimura, K., Saiki, R., Okudaira, H., Tome, M., Higashi, K., Nakamura, M., Terui, Y., Fujiwara, K., Kashiwagi, K., and Igarashi, K.: Role of polyamines at the G1/S boundary and G2/M phase of the cell cycle. Int. J. Biochem. Cell Biol. 45, 1042-1050 (2013)
  6. Saiki, R., Yoshizawa, Y., Minarini, A., Milelli, A., Marchetti, C., Tumiatti, V., Toida, T., Kashiwagi, K., Igarashi, K.: In vitro and in vivo evaluation of polymethylene tetraamine derivatives as NMDA receptor channel blockers. Bioorg. Med. Chem. Lett. 23, 3901-3904 (2013)
  7. Uemura, T., Tanaka, Y., Higashi, K., Miyamori, D., Takasaka, T., Nagano, T., Toida, T., Yoshimoto, K., Igarashi, K., Ikegaya, H.: Acetaldehyde-induced cytotoxicity involves induction of spermine oxidase at the transcriptional level. Toxicology 9, 1-7 (2013)
  8. Zhao, X., Yang, B., Solakyildirim, K., Joo, E. J., Toida, T., Higashi, K., Linhardt, R.J., Li, L.: Sequence analysis and domain motifs in the porcine skin decorin glycosaminoglycan chain. J. Biol. Chem. 288, 9226-9237 (2013)
2012
  1. Ishii, I., Suzuki, T., Kaneko, H., Uchida, M., Suzuki, Y., Higashi, K., Yagi, S., Ariyoshi, N., Igarashi, K., and Kitada, M.: Correlation between antizyme 1 and differentiation of vascular smooth muscle cells cultured in honeycomb-like type-I collagen matrix. Amino Acids 42, 565-575 (2012)
  2. Tomitori, H., Suganami, A., Saiki, R., Mizuno, S., Yoshizawa, Y., Masuko, T., Tamura, Y., Nishimura, K., Toida, T., Williams, K., Kashiwagi, K., and Igarashi, K.: Structural change of R domain heterodimer of NMDA receptor GluN1 and GluN2B through binding of spermine and ifenprodil. J. Pharmacol. Exp. Ther. 343, 82-90 (2012)
  3. Yoshida, M., Mikami, T., Higashi, K., Saiki, R., Mizoi, M., Fukuda, K., Nakamura, T., Ishii, I., Nishimura, K., Toida, T., Tomitori, H., Kashiwagi, K., and Igarashi, K.: Inverse correlation between stroke and urinary 3-hydroxypropyl mercapturic acid, an acrolein-glutathione metabolite. Clin. Chim. Acta 413, 753-759 (2012)
  4. Nishimura, K., Lee, S. B., Park, J. H., and Park, M. H.: Essential role of eIF5A-1 and deoxyhypusine synthase in mouse embryonic development. Amino Acids 42, 703-710 (2012)
  5. Higashi, K., Hosoyama, S., Ohno, A., Masuko, S., Yang, B., Sterner, E., Wang, Z., Linhardt, R. J., and Toida, T.: Photochemical preparation of a novel low molecular weight heparin. Carbohydr Polym. 87, 1737-1743 (2012)
  6. Matsumoto, A., Hosoyama, S., Higashi, K., and Toida, T.: Simultaneous determination of uronates found in polysaccharides from natural products by HPLC with fluorometric detection. Carbohydr. Res. 358, 82-8 (2012)
2011
  1. Ishii, I., Suzuki, T., Kaneko, H., Uchida, M., Suzuki, Y., Higashi, K., Yagi, S., Ariyoshi, N., Igarashi, K., Kitada, M.: Correlation between antizyme 1 and differentiation of vascular smooth muscle cells cultured in honeycomb-like type-I collagen matrix. Amino Acids 42, 565-575 (2011)
  2. Ly, M., Leach, F. E. 3rd, Laremore, T. N., Toida, T., Amster, I. J., Linhardt, R. J.: The proteoglycan bikunin has a defined sequence. Nat. Chem. Biol. 7, 827-833 (2011)
  3. Higashi, K., Ly, M., Wang, Z., Masuko, S., Bhaskar, U., Sterner, E., Zhang, F., Toida, T., Dordick, J. S., Linhardt, R. J.: Controlled Photochemical Depolymerization of K5 Heparosan, a Bioengineered Heparin Precursor. Carbohydr. Polym. 86, 1365-1370 (2011)
  4. Masuko, S., Higashi, K., Wang, Z., Bhaskar, U., Hickey, A. M., Zhang, F., Toida, T., Dordick, J. S., Linhardt, R. J.: Ozonolysis of the double bond of the unsaturated uronate residue in low-molecular-weight heparin and K5 heparosan. Carbohydr. Res. 346, 1962-1966 (2011)
  5. Hamdan, F.F., Gauthier, J., Araki, Y., Lin, D.T., Yoshizawa, Y., Higashi, K., Park, A.R., Spiegelman, D., Dobrzeniecka, S., Piton, A., Tomitori, H., Daoud, H., Massicotte, C., Henrion, E., Diallo, O; S2D Group, Shekarabi, M., Marineau, C., Shevell, M., Maranda, B., Mitchell, G., Drapeau, P., Lacaille, J.C., Kim, E., Lee, J.R., Igarashi, K., Huganir, R.L., Rouleau, G.A., Michaud, J.L.: Excess of de novo deleterious mutations in genes associated with glutamatergic systems in nonsyndromic intellectual disability. Am. J. Hum. Genet. 88, 306-316 (2011)
  6. Seto, Y., Ochi, M., Igarashi, N., Inoue, R., Oishi, A., Toida, T., Yamada, S., Onoue, S.: In vitro photobiochemical characterization of sulfobutylether-β-cyclodextrin formulation of bufexamac. J. Pharm. Biomed. Anal. 55, 591-596 (2011)
  7. Saiki, R., Park, H., Ishii, I., Yoshida, M., Nishimura, K., Toida, T., Tatsukawa, H., Kojima, S., Ikeguchi, Y., Pegg, A. E., Kashiwagi, K., Igarashi, K.: Brain infarction correlates more closely with acrolein than with reactive oxygen species. Biochem. Biophys. Res. Commun. 404, 1044-1049 (2011)
2010
  1. Park, M. H., Nishimura, K., Zanelli, C. F., and Valentini, S. R.: Functional significance of eIF5A and its hypusine modification in eukaryotes. Amino Acids 38, 491-500 (2010) (Review)
  2. Terui, Y., Tabei, Y., Akiyama, M., Higashi, K., Tomitori, H., Yamamoto, K., Ishihama, A., Igarashi, K., Kashiwagi, K.: Ribosome modulation factor, an important protein for cell viability encoded by the polyamine modulon. J. Biol. Chem. 285, 28698-28707 (2010)
  3. Higashi, K., Sakamaki, Y., Herai, E., Demizu, R., Uemura, T., Saroj, S. D., Zenda, R., Terui, Y., Nishimura, K., Toida, T., Kashiwagi, K., Igarashi, K.: Identification and functions of amino acid residues in PotB and PotC involved in spermidine uptake activity. J. Biol. Chem. 285, 39061-39069 (2010)
  4. Uchida, M., Ishii, I., Inoue, C., Akisato, Y., Watanabe, K., Hosoyama, S., Toida, T., Ariyoshi, N., Kitada, M.: Kefiran Reduces Atherosclerosis in Rabbits Fed a High Cholesterol Diet. J. Atheroscler Thromb. 17, 980-988 (2010)
  5. Burana-osot, J., Pattanapanyasat, K., Soonthornchareonnon, N., Sukapirom, K. Toida, T.: Characterization and immuno-stimulating activity of polysaccharides from Thai medicinal plants. Nat. Prod. Res. 24, 1403-1412 (2010)
  6. Yoshida, M., Higashi, K., Kobayashi, E., Saeki, N., Wakui, K., Kusaka, T., Takizawa, H., Kashiwado, K., Suzuki, N., Fukuda, K., Nakamura, T., Watanabe, S., Tada, K., Machi, Y., Mizoi, M., Toida, T., Kanzaki, T., Tomitori, H., Kashiwagi, K., Igarashi, K.: Correlation between images of silent brain infarction, carotid atherosclerosis and white matter hyperintensity, and plasma levels of acrolein, IL-6 and CRP. Atherosclerosis, 211, 475-479 (2010)
  7. Joo, E. J.,, Hui, Y., Park, Y., Park, N. Y., Toida, T., Linhardt, R. J., Kim, Y. S.: Induction of Nucleolin Translocation by Acharan Sulfate in A549 Human Lung Adenocarcinoma. J. Cell Biochem. 110, 1272-1278 (2010)
  8. Burana-Osot, J., Soonthornchareonnon, N., Chaidedgumjorn, A., Hosoyama, S, Toida, T.: Determination of galacturonic acid from pomelo pectin in term of galactose by HPAEC with fluorescence detection. Carbohydr. Polym. 81, 461–465 (2010)
  9. Burana-Osot, J., Soonthornchareonnon, N., Hosoyama, S., Linhardt, R.J., Toida, T.: Partial depolymerization of pectin by a photochemical reaction. Carbohydr. Res. 345, 1205-1210 (2010)
  10. Higashi, K, .Yoshida, M., Igarashi, A., Ito, K., Wada, Y., Murakami, S., Kobayashi, D., Nakano, M., Sohda, M., Nakajima, T., Narita, I., Toida, T, Kashiwagi, K., Igarashi, K.: Intense correlation between protein-conjugated acrolein and primary Sjögren's syndrome. Clin. Chim. Acta, 411, 359-363 (2010)
  11. Yoshida, M., Higashi, K., Jin, L, Machi, Y., Suzuki, T., Masuda, A., Dohmae, N., Suganami, A., Tamura, Y., Nishimura, K., Toida, T., Tomitori, H., Kashiwagi, K., Igarashi, K.: Identification of acrolein-conjugated protein in plasma of patients with brain infarction. Biochem. Biophys. Res. Commun. 391, 1234-1239 (2010)
2009
  1. Uemura, T., Higashi, K., Takigawa, M., Toida, T., Kashiwagi, K., Igarashi, K.: Polyamine - modulon in yeast - stimulation of COX4 synthesis by spermidine at the level of translation. Int. J. Biochem. Cell Biol. 41, 2538-2545 (2009)
  2. Saiki, R., Nishimura, K., Ishii, I., Omura, T., Okuyama, S., Kashiwagi, K., Igarashi, K.: Intense correlation between brain infarction and protein-conjugated acrolein. Stroke 40, 3356-3361 (2009)
  3. Nishimura, K., Okudaira, H., Ochiai, E., Higashi, K., Kaneko, M., Ishii, I., Nishimura, T., Dohmae, N., Kashiwagi, K., Igarashi, K.: Identification of proteins whose synthesis is preferentially enhanced by polyamines at the level of translation in mammalian cells. Int. J. Biochem. Cell Biol. 41, 2251-2261 (2009)
  4. Terui, Y., Higashi, K., Tabei, Y., Tomitori, H., Yamamoto, K., Ishihama, A., Igarashi, K., Kashiwagi, K.: Enhancement of the synthesis of RpoE and StpA by polyamines at the level of translation in Escherichia coli under heat shock conditions. J. Bacteriol. 191, 5348-5357 (2009)
  5. Yoshida, M., Tomitori, H., Machi, Y., Katagiri, D., Ueda, S., Horiguchi, K., Kobayashi, E., Saeki, N., Nishimura, K., Ishii, I., Kashiwagi, K., Igarashi, K.: Acrolein, IL-6 and CRP as markers of silent brain infarction. Atherosclerosis 203, 557-562 (2009)
  6. Yoshida, M., Tomitori, H., Machi, Y., Hagihara, M., Higashi, K., Goda, H., Ohya, T., Niitsu, M., Kashiwagi, K., Igarashi, K.: Acrolein toxicity: comparison with reactive oxygen species. Biochem. Biophys. Res. Commun. 378, 313-318 (2009)
  7. Masuda, Y., Matsumoto, A., Toida, T., Oikawa, T., Ito, K., Nanba, H.: Characterization and antitumor effect of a novel polysaccharide from Grifola frondosa. J. Agric. Food. Chem. 57, 10143-10149 (2009)
  8. Burana-osot, J., Hosoyama, S., Nagamoto, Y., Suzuki, S., Linhardt, R. J., Toida, T.: Photolytic depolymerization of alginate. Carbohydr Res. 344, 2023-2027 (2009)
  9. Toida, T., Sato, K., Hosoyama, S., Sakamoto, N., Linhardt, R. J.: Solvolytic depolymerization of chondroitin and dermatan sulfates. Carbohydr. Res. 344, 888-893 (2009)
  10. Ogura, Y., Kitaguchi, T., Ishiwata, K., Suzuki, N., Toida T., Suzuki K. T.: Speciation of selenomethionine metabolites in wheat germ extract. Metallomics 1, 78-86 (2009)
  11. Zhang, F., Zhang, Z., Thistle, R., McKeen, L., Hosoyama, S., Toida, T., Linhardt R. J., Page-McCaw P.: Structural characterization of glycosaminoglycans from zebrafish in different ages. Glycoconj J. 26, 211-218 (2009)