千葉大学・ファイトケミカル植物分子科学:研究成果



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1. 原著論文

2016

  1. Toyotome, T., Takahashi, H., and Kamei, K.: MEIS3 is repressed in A549 lung epithelial cell by deoxynivalenol and the repression contributes to the deleterious effect. J Toxicol Sci. 41(1), 25-31 (2016)
  2. Kusuya, Y., Sakai, K., Takahashi, H., and Yaguchi, T.: Draft genome sequence of the pathogenic filamentous fungus Aspergillus lentulus IFM 54703T. Genome Announc. 4(1) (2016)
  3. Taketo Okada*, Farit Mochamad Afendi*, Mami Yamazaki*, Kaori Nakahashi Chida, Makoto Suzuki, Rika Kawai, Miyuki Kim, Takao Namiki, Shigehiko Kanaya, and Kazuki Saito (*equal contribution): Informatics framework of traditional Sino-Japanese medicine (Kampo) unveiled by factor analysis. J. Nat. Med., 70, 107-114, DOI: 10.1007/s11418-015-0946-0 (2016)
  4. Kotaro Yamamoto, Katsutoshi Takahashi, Hajime Mizuno, Aya Anegawa, Kimitsune Ishizaki, Hidehiro Fukaki, Miwa Ohnishi, Mami Yamazaki, Tsutomu Masujima, Tetsuro Mimura: Cell-specific localization of alkaloids in Catharanthus roseus stem tissue measured with Imaging MS and Single cell MS. Proc Natl. Acad. Sci. USA, 113, 3891–3896 (2016)
  5. Rai, A., Yamazaki, M., Takahashi, H., Nakamura, M., Kojoma, M., Suzuki, H., and Saito, K.: RNA-seq transcriptome analysis of Panax japonicus, and its comparison with other Panax species to identify potential genes involved in the saponins biosynthesis. Front Plant Sci. 7, 481 (2016)
  6. Rohani, R. E., Chiba, M., Kawaharada, M., Asano, T., Oshima, Y., Mitsuda, N., Ohme-Takagi, M., Fukushima, A., Rai, A., and Saito, K., Yamazaki, M.: An MYB transcription factor regulating specialized metabolisms in Ophiorrhiza pumila. Plant Biotechnology, 33, 1-9 (2016)
  7. Han, R., Rai, A., Nakamura, M., Suzuki, H., Takahashi, H., Yamazaki, M., and Saito, K.: De Novo Deep Transcriptome Analysis of Medicinal Plants for Gene Discovery in Biosynthesis of Plant Natural Products. Methods in Enzymology 572, 1-27 (2016)
  8. Rai, A., Umashankar S, Megha, Kiat L.B, Johanan A.S.B, and Swarup S: TT8 affects innate immunity in Arabidopsis by reprogramming hormone biosynthesis and glycosylation of metabolites. Plant Physiology (2016). in press
  9. Rai A, Nakamura M, Takahashi H, Suzuki H, Saito K, and Yamazaki: M De novo assembly and characterization of Swertia japonica transcriptome for the identification of candidate genes involved in the biosynthesis of therapeutic metabolites. Plant Cell Report (2016). in press
  10. Rai A, Kamochi H, Suzuki H, Nakamura M, Takahashi H, Saito K, and Yamazaki M De novo transcriptome assembly and characterization of nine tissues of Lonicera japonica to identify potential candidate genes involved in chlorogenic acid, luteolosides, and secoiridoid biosynthesis pathways. Journal of Natural Medicines (2016). in press
  11. Ryo Nakabayashi, Hiroshi Tsugawa, Mariko Kitajima, Hiromitsu Takayama, and Kazuki Saito: Boosting sensitivity in liquid chromatography–Fourier transform ion cyclotron resonance–tandem mass spectrometry for product ion analysis of monoterpene indole alkaloids. Front. Plant Sci., doi: 10.3389/fpls.2015.01127 (2016)
  12. Ryo Nakabayashi, Yuji Sawada, Morihiro Aoyagi, Yutaka Yamada, Masami Yokota Hirai, Tetsuya Sakurai, Takahiro Kamoi, Daryl D, Rowan, and Kazuki Saito: Chemical assignment of structural isomers of sulfur-containing metabolites in garlic by liquid chromatography-Fourier transform ion cyclotron resonance-mass spectrometry. J. Nutrition, 146, in press, doi: 10.3945/jn.114.202317 (2016)
  13. Yuko Ogo, Tetsuya Mori, Ryo Nakabayashi, Kazuki Saito, and Fumio Takaiwa: Transgenic rice seed expressing flavonoid biosynthetic genes accumulate glycosylated and/or acylated flavonoids in protein bodies. J. Exp. Bot., 67, 95-106, DOI: 10.1093/jxb/erv429 (2016)
  14. Zhigang Yang, Ryo Nakabayashi, Tetsuya Mori, Satoshi Takamatsu, Susumu Kitanaka, and Kazuki Saito: Metabolome analysis of Oryza sativa (rice) using liquid chromatography-mass spectrometry for characterizing organ specificity of flavonoids with anti-inflammatory and anti-oxidant activity. Chem. Pharm. Bull., 64, 952-956 (2016)
  15. Miyako Kusano, Makoto Kobayashi, Yumiko Iizuka, Atsushi Fukushima, and Kazuki Saito: Unbiased profiling of volatile organic compounds in the headspace of Allium plants using an in-tube extraction device. BMC Res Notes. 9, 133. doi: 10.1186/s13104-016-1942-5 (2016)
  16. Yoshiko Toyosawa, Yasushi Kawagoe, Ryo Matsushima, Naoko Crofts, Masahiro Ogawa, Masako Fukuda, Toshihiro Kumamaru, Yozo Okazaki, Miyako Kusano, Kazuki Saito, Kiminori Toyooka, Mayuko Sato, Yongfeng Ai, Jay-Lin Jane, Yasunori Nakamura, and Naoko Fujita: Deficiency of starch synthase IIIa and IVb alters starch granule morphology from polyhedral to spherical in rice endosperm. Plant Physiol., in press, doi: http://dx.doi.org/10.1104/pp.15.01232 (2016)
  17. Naoyuki Umemoto, Masaru Nakayasu, Kiyoshi Ohyama, Mari Yotsu-Yamashita, Masaharu Mizutani, Hikaru Seki, Kazuki Saito, and Toshiya Muranaka: Two cytochrome P450 monooxygenases catalyze early hydroxylation steps in the potato steroid glycoalkaloid biosynthetic pathway. Plant Physiol., in press doi:10.1104/pp.16.00137 (2016)
  18. Somnuk Bunsupa, Kosuke Hanada, Akira Maruyama, Kaori Aoyagi, Kana Komatsu, Hideki Ueno, Madoka Yamashita, Ryosuke Sasaki, Akira Oikawa, Kazuki Saito, and Mami Yamazaki: Molecular evolution and functional characterization of a bifunctional decarboxylase involved in Lycopodium alkaloid biosynthesis. Plant Physiol., in press doi:10.1104/pp.16.00639 (2016)
  19. Hagiwara, D., Takahashi, H., Fujimoto, M., Sugahara, M., Misawa, Y., Gonoi, T., Itoyama, S., Watanabe, A., and Kamei, K.: Multi-azole resistant Aspergillus fumigatus harboring Cyp51A TR46/Y121F/T289A isolated in Japan. J Infect Chemother. (2016) in press.
  20. Hagiwara, D., Takahashi, H., Kusuya, Y., Kawamoto, S., Kamei, K., and Gonoi, T.: Comparative transcriptome analysis revealing dormant conidia and germination associated genes in Aspergillus species: An essential role for AtfA in conidial dormancy. BMC Genomics (2016) in press.
  21. Maryam Nasr Esfahani, Miyako Kusano, Kien Huu Nguyen, Yasuko Watanabe, Chien Van Ha, Kazuki Saito, Saad Sulieman, Luis Herrera-Estrella, and Lam-Son Phan Tran: Adaptation of the symbiotic Mesorhizobium–chickpea relationship to phosphate deficiency relies on reprogramming of whole plant metabolism. Proc. Natl. Acad. Sci. USA, in press (2016)
  22. Takayuki Tohge, Regina Wendenburg, Hirofumi Ishihara, Ryo Nakabayashi, Mutsumi Watanabe, Ronan Sulpice, Rainer Hoefgen, Hiromitsu Takayama, Kazuki Saito, Mark Stitt, Alisdair R. Fernie: Characterization of a recently evolved flavonol phenylacyltransferase gene provides signatures of natural light selection in Brassicaceae. Nature Commun., in press (2016)
  23. Takanashi, N., Suzuki, K., Kitajima, M,. and Takayama, H.: Total synthesis of conolidine and apparicine. Tetrahedron Lett. 57, 375–378 (2016)
  24. Kitajima, M., Watanabe, K., Maeda, H., Kogure, N., and H. Takayama: Asymmetric total synthesis of sarpagine-related indole alkaloids hydroxygardnerine, hydroxygardnutine, gardnerine, (E)-16-epi-normacusine B, and koumine. Org. Lett. 18, 1912–1915 (2016)
  25. Kogure, N., Maruyama, M., Wongseripipatana, S., Kitajima, M., and Takayama, H.: New lycopodine-type alkaloids from Lycopodium carinatum. Chem. Pharm. Bull. 64, 793¬–799 (2016)
  26. Tokuda, R., Okamoto, Y., Koyama, T., Kogure, N., Kitajima, M., and Takayama, H.: Asymmetric total synthesis of kopsiyunnanine K, a monoterpenoid indole alkaloid with a rearranged skeleton. Org. Lett., 18, in press (2016)
  27. Fujita, K., Sugiyama, R., Nishimura, S., Ishikawa, N., Arai, M. A., Ishibashi, M., and Kakeya, H.: Stereochemical assignment and biological evaluation of BE-14106 unveils the importance of one acetate unit for the antifungal activity of polyene macrolactams. J. Nat. Prod. in press.
  28. Yoneyama, T., Arai, M. A., Koyano, T., Kowithayakorn, T., and Ishibashi, M.: Isolation and evaluation of hedgehog inhibitors from Christmas grass (Themeda arguens). Heterocycles in press.
  29. Arai, M. A., Kofuji, Y., Tanaka, Y., Yanase, N., Yamaku, K., Fuentes, R. G., Karmakar, U. K., and Ishibashi, M.: Synthesis of rocaglamide derivatives and evaluation of their Wnt signal inhibitory activities. Org. Biomol. Chem. 14, 3061-3068 (2016)
  30. Ahmed, F., Toume, K., Ishikawa, N., Arai, M. A., Sadhu, S. K., and Ishibashi, M.: Constituents from Entada scandens with TRAIL-resistance overcoming activity. Nat. Prod. Commun. in press.
  31. Abdelfattah, M. S., Ishikawa, N., Karmakar, U. K., Yamaku, K., and Ishibashi, M.: New phenazine analogues from Streptomyces sp. IFM 11694 with Wnt signaling inhibitory and TRAIL resistance-overcoming activities. J. Antibiot. in press.
  32. Karmakar, U. K., Toume, K., Ishikawa, N., Arai, M. A., Sadhu, S. K., Ahmed, F., and Ishibashi, M.: Bioassay-guided isolation of compounds with TRAIL-resistance overcoming activity from Datura stramonium. Nat. Prod. Commun. 11, 185-187 (2016)
  33. Arai, M. A., Ishikawa, N., Tanaka, M., Uemura, K., Sugimitsu, N., Koyano, T., Kowithayakorn, T., and Ishibashi, M.: Hes1 dimer inhibitor isolated by target protein oriented natural products isolation (TPO-NAPI) of differentiation activators of neural stem cells. Chem. Sci. 7, 1514-1520 (2016)
  34. Abdelfattah, M. S., Ishikawa, N., Karmakar, U. K., and Ishibashi, M.: Sulfotanone, a new alkyl sulfonic acid derivative from Streptomyces sp. IFM 11694 with TRAIL resistance-overcoming activity. J. Nat. Med. 70, 266-270 (2016)
  35. E. Goto, K. Hayashi, S. Furuyama, S. Hikosaka and Y. Ishigami. Effect of UV light on phytochemical accumulation and expression of anthocyanin biosynthesis genes in red leaf lettuce. Acta Hort.ic 1134: 179-185. (2016)
  36. E. Goto, Y. Ishigami and L. Okushima. Development of a greenhouse simulation model to estimate energy and resources necessary for environmental controls under various climate conditions . Acta Hortic. in press (2016)
  37. Kobayashi, Y., Ando, H., Hanaoka, M., and Tanaka, K.: Abscisic acid participates in the control of cell-cycle initiation through heme homeostasis in the unicellular red alga Cyanidioschyzon merolae. Plant Cell Physiol., 57, 953-960 (2016)
  38. Tewolde, F.T., Lu, N., Shiina, K., Maruo, T., Takagaki, M., Kozai, T., Yamori, W.: Nighttime Supplemental LED Inter-lighting Improves Growth and Yield of Single-truss Tomatoes by Enhancing Photosynthesis in Both Winter and Summer. Frontiers in Plant Science 7, 448 (2016)
  39. Watanabe, C.K.A., Yamori, W., Takahashi, S., Terashima, I., Noguchi, K.: Mitochondrial Alternative Pathway-Associated Photoprotection of Photosystem II is Related to the Photorespiratory Pathway. Plant and Cell Physiology (2016)
  40. Kagawa, N., Nibbs, A. E., and Rawal, V. H.: One-carbon homologation of primary alcohols to carboxylic acids, esters, and amides via Mitsunobu reactions with MAC reagents. Organic Letters 18, 2363–2366 (2016)
  41. Okazaki, Yozo; Saito, Kazuki: Integrated metabolomics and phytochemical genomics approaches for studies on rice. GIGASCIENCE, 5, 11 (2016)
  42. Rohani, Emelda Rosseleena; Chiba, Motoaki; Kawaharada, Miki; Asano, Takashi; Oshima, Yoshimi; Mitsuda, Nobutaka; Ohme-Takagi, Masaru; Fukushima, Atsushi; Rai, Amit; Saito, Kazuki; Yamazaki, Mami: An MYB transcription factor regulating specialized metabolisms in Ophiorrhiza pumila. 33, 1 (2016)
  43. Edison, Arthur S.; Hall, Robert D.; Junot, Christophe; Karp, Peter D.; Kurland, Irwin J.; Mistrik, Robert; Reed, Laura K.; Saito, Kazuki; Salek, Reza M.; Steinbeck, Christoph; Sumner, Lloyd W.; Viant, Mark R.: The Time Is Right to Focus on Model Organism Metabolome. METABOLITES, 6 (2016)
  44. Toyosawa, Yoshiko; Kawagoe, Yasushi; Matsushima, Ryo; Crofts, Naoko; Ogawa, Masahiro; Fukuda, Masako; Kumamaru, Toshihiro; Okazaki, Yozo; Kusano, Miyako; Saito, Kazuki; Toyooka, Kiminori; Sato, Mayuko; Ai, Yongfeng; Jane, Jay-Lin; Nakamura, Yasunori; Fujita, Naoko: Deficiency of Starch Synthase IIIa and IVb Alters Starch Granule Morphology from Polyhedral to Spherical in Rice Endosperm. PLANT PHYSIOLOGY, 170, 1255-1270 (2016)
  45. Nuoendagula; Kamimura, Naofumi; Mori, Tetsuya; Nakabayashi, Ryo; Tsuji, Yukiko; Hishiyama, Shojiro; Saito, Kazuki; Masai, Eiji; Kajita, Shinya: Expression and functional analyses of a putative phenylcoumaran benzylic ether reductase in Arabidopsis thaliana. PLANT CELL REPORTS, 35, 513-526 (2016)
  46. Araki, Takeshi; Saga, Yusuke; Marugami, Momo; Otaka, Junnosuke; Araya, Hiroshi; Saito, Kazuki; Yamazaki, Mami; Suzuki, Hideyuki; Kushiro, Tetsuo: Onocerin Biosynthesis Requires Two Highly Dedicated Triterpene Cyclases in a Fern Lycopodium clavatum. CHEMBIOCHEM, 17, 288-290 (2016)
  47. Rai, Amit; Saito, Kazuki: Omics data input for metabolic modelling, CURRENT OPINION IN BIOTECHNOLOGY, 37, 127-134 (2016)
  48. Nakabayashi, Ryo; Sawada, Yuji; Aoyagi, Morihiro; Yamada, Yutaka; Hirai, Masami Yokota; Sakurai, Tetsuya; Kamoi, Takahiro; Rowan, Daryl D.; Saito, Kazuki: Chemical Assignment of Structural Isomers of Sulfur-Containing Metabolites in Garlic by Liquid Chromatography Fourier Transform Ion Cyclotron Resonance Mass Spectrometry. JOURNAL OF NUTRITION, 146, 397S-402S (2016)
  49. Nakamura, Shinya; Hondo, Kana; Kawara, Tomoko; Okazaki, Yozo; Saito, Kazuki; Kobayashi, Kappei; Yaeno, Takashi; Yamaoka, Naoto; Nishiguchi, Masamichi: Conferring high-temperature tolerance to nontransgenic tomato scions using graft transmission of RNA silencing of the fatty acid desaturase gene. PLANT BIOTECHNOLOGY JOURNAL, 14, 783-790 (2016)
  50. Okada, Taketo; Afendi, Farit Mochamad; Yamazaki, Mami; Chida, Kaori Nakahashi; Suzuki, Makoto; Kawai, Rika; Kim, Miyuki; Namiki, Takao; Kanaya, Shigehiko; Saito, Kazuki: Informatics framework of traditional Sino-Japanese medicine (Kampo) unveiled by factor analysis. JOURNAL OF NATURAL MEDICINES, 70, 107-114 (2016)
  51. Ogo, Yuko; Mori, Tetsuya; Nakabayashi, Ryo; Saito, Kazuki; Takaiwa, Fumio: Transgenic rice seed expressing flavonoid biosynthetic genes accumulate glycosylated and/or acylated flavonoids in protein bodies. JOURNAL OF EXPERIMENTAL BOTANY, 67, 95-106 (2016)
  52. Toyotome, Takahito; Takahashi, Hiroki; Kamei, Katsuhiko, MEIS3 is repressed in A549 lung epithelial cells by deoxynivalenol and the repression contributes to the deleterious effect. JOURNAL OF TOXICOLOGICAL SCIENCES, 41, 25-31 (2016)
  53. Hirata, Hiroshi; Ohnishi, Toshiyuki; Tomida, Kensuke; Ishida, Haruka; Kanda, Momoyo; Sakai, Miwa; Yoshimura, Jin; Suzuki, Hideyuki; Ishikawa, Takamasa; Dohra, Hideo; Watanabe, Naoharu: Seasonal induction of alternative principal pathway for rose flower scent. SCIENTIFIC REPORTS, 6, 20234 (2016)
  54. Takanashi, Noriyuki; Suzuki, Kenta; Kitajima, Mariko; Takayama, Hiromitsu: Total synthesis of conolidine and apparicine. TETRAHEDRON LETTERS, 57, 375-378 (2016)
  55. Karmakar, Utpal K.; Toume, Kazufumi; Ishikawa, Naoki; Arai, Midori A.; Sadhu, Samir K.; Ahmed, Firoj; Ishibashi, Masami: Bioassay-Guided Isolation of Compounds from Datura stramonium with TRAIL-Resistance Overcoming Activity. NATURAL PRODUCT COMMUNICATIONS, 11, 185-187 (2016)
  56. Ahmed, Firoj; Ishibashi, Masami: Bio-active Natural Products with TRAIL-Resistance Overcoming Activity. CHEMICAL & PHARMACEUTICAL BULLETIN, 64, 119-127 (2016)
  57. Arai, Midori A.; Kofuji, Yuuki; Tanaka, Yuuki; Yanase, Natsuki; Yamaku, Kazuki; Fuentes, Rolly G.; Karmakar, Utpal Kumar; Ishibashi, Masami: Synthesis of rocaglamide derivatives and evaluation of their Wnt signal inhibitory activities. ORGANIC & BIOMOLECULAR CHEMISTRY, 14, 3061-3068 (2016)
  58. Arai, Midori A.; Ishikawa, Naoki; Tanaka, Mitsuha; Uemura, Kenji; Sugimitsu, Noriko; Suganami, Akiko; Tamura, Yutaka; Koyano, Takashi; Kowithayakorn, Thaworn; Ishibashi, Masami: Hes1 inhibitor isolated by target protein oriented natural products isolation (TPO-NAPI) of differentiation activators of neural stem cells. CHEMICAL SCIENCE, 7, 1514-1520 (2016)
  59. Yamori, Wataru; Makino, Amane; Shikanai, Toshiharu: A physiological role of cyclic electron transport around photosystem I in sustaining photosynthesis under fluctuating light in rice. SCIENTIFIC REPORTS, 6, 20147 (2016)
  60. Yamori, Wataru; Shikanai, Toshiharu: Physiological Functions of Cyclic Electron Transport Around Photosystem I in Sustaining Photosynthesis and Plant Growth. ANNUAL REVIEW OF PLANT BIOLOGY, VOL 67, 67, 81-106 (2016)
  61. Yamori, Wataru; Kondo, Eri; Sugiura, Daisuke; Terashima, Ichiro; Suzuki, Yuji; Makino, Amane: Enhanced leaf photosynthesis as a target to increase grain yield: insights from transgenic rice lines with variable Rieske FeS protein content in the cytochrome b(6)/f complex. PLANT CELL AND ENVIRONMENT, 39, 80-87 (2016)

2015

  1. Nakabayashi, Ryo; Tsugawa, Hiroshi; Kitajima, Mariko; Takayama, Hiromitsu; Saito, Kazuki: Boosting Sensitivity in Liquid Chromatography-Fourier Transform Ion Cyclotron Resonance-Tandem Mass Spectrometry for Product Ion Analysis of Monoterpene Indole Alkaloids. FRONTIERS IN PLANT SCIENCE, 6, 1127 (2015)
  2. Maekawa, Mikika; Honoki, Rina; Ihara, Yuta; Sato, Ryoichi; Oikawa, Akira; Kanno, Yuri; Ohta, Hiroyuki; Seo, Mitsunori; Saito, Kazuki; Masuda, Shinji: Impact of the plastidial stringent response in plant growth and stress responses. NATURE PLANTS, 1, UNSP 15167 (2015)
  3. Abdelrahman, Mostafa; Sawada, Yuji; Nakabayashi, Ryo; Sato, Shusei; Hirakawa, Hideki; El-Sayed, Magdi; Hirai, Masami Yokota; Saito, Kazuki; Yamauchi, Naoki; Shigyo, Masayoshi: Integrating transcriptome and target metabolome variability in doubled haploids of Allium cepa for abiotic stress protection. MOLECULAR BREEDING, 35, 195 (2015)
  4. Fiehn, Oliver; Putri, Sastia P.; Saito, Kazuki; Salek, Reza M.; Creek, Darren J.: Metabolomics continues to expand: highlights from the 2015 metabolomics conference. METABOLOMICS, 11, 1036-1040 (2015)
  5. Suzuki, Mami; Nakabayashi, Ryo; Mori, Tetsuya; Saito, Kazuki; Shiratake, Katsuhiro: The metabolic profile of grape berry skin and a comparison of metabolomes before veraison and at harvest. PLANT BIOTECHNOLOGY, 32, 267-272 (2015)
  6. Yoshimoto, Naoko; Onuma, Misato; Sugino, Yuka; Nakabayashi, Ryo; Imai, Shinsuke; Tsuneyoshi, Tadamitsu; Sumi, Shin-ichiro; Saito, Kazuki: Identification of a flavin-containing S-oxygenating monooxygenase involved in alliin biosynthesis in garlic. PLANT JOURNAL, 83, 941-951 (2015)
  7. Okazaki, Yozo; Nishizawa, Tomoko; Takano, Kouji; Ohnishi, Miwa; Mimura, Tetsuro; Saito, Kazuki: Induced accumulation of glucuronosyldiacylglycerol in tomato and soybean under phosphorus deprivation. PHYSIOLOGIA PLANTARUM, 155, SI, 33-42 (2015)
  8. Takayama, Mariko; Koike, Satoshi; Kusano, Miyako; Matsukura, Chiaki; Saito, Kazuki; Ariizumi, Tohru; Ezura, Hiroshi: Tomato Glutamate Decarboxylase Genes SlGAD2 and SlGAD3 Play Key Roles in Regulating gamma-Aminobutyric Acid Levels in Tomato (Solanum lycopersicum). PLANT AND CELL PHYSIOLOGY, 56, 1533-1545 (2015)
  9. Oikawa, Akira; Otsuka, Takao; Nakabayashi, Ryo; Jikumaru, Yusuke; Isuzugawa, Kanji; Murayama, Hideki; Saito, Kazuki; Shiratake, Katsuhiro: Metabolic Profiling of Developing Pear Fruits Reveals Dynamic Variation in Primary and Secondary Metabolites, Including Plant Hormones. PLOS ONE, 10, e0131408 (2015)
  10. Clevenger, Josh P.; Van Houten, Jason; Blackwood, Michelle; Rodriguez, Gustavo Ruben; Jikumaru, Yusuke; Kamiya, Yuji; Kusano, Miyako; Saito, Kazuki; Visa, Sofia; van der Knaap, Esther: Network Analyses Reveal Shifts in Transcript Profiles and Metabolites That Accompany the Expression of SUN and an Elongated Tomato Fruit. PLANT PHYSIOLOGY, 168, 1164 (2015)
  11. Han, Rongchun; Takahashi, Hiroki; Nakamura, Michimi; Yoshimoto, Naoko; Suzuki, Hideyuki; Shibata, Daisuke; Yamazaki, Mami; Saito, Kazuki: Transcriptomic landscape of Pueraria lobata demonstrates potential for phytochemical study. FRONTIERS IN PLANT SCIENCE, 6, 426 (2015)
  12. Fukushima, Atsushi; Nakamura, Michimi; Suzuki, Hideyuki; Saito, Kazuki; Yamazaki, Mami: High-Throughput Sequencing and De Novo Assembly of Red and Green Forms of the Perilla frutescens var. crispa Transcriptome. PLOS ONE, 10, e0129154 (2015)
  13. Han, Rongchun; Takahashi, Hiroki; Nakamura, Michimi; Bunsupa, Somnuk; Yoshimoto, Naoko; Yamamoto, Hirobumi; Suzuki, Hideyuki; Shibata, Daisuke; Yamazaki, Mami; Saito, Kazuki: Transcriptome Analysis of Nine Tissues to Discover Genes Involved in the Biosynthesis of Active Ingredients in Sophora flavescens. BIOLOGICAL & PHARMACEUTICAL BULLETIN, 38, 876-883 (2015)
  14. Hayakawa, Yoshinori; Duan, Zhongrui; Yadake, Miki; Tsukano, Jun; Yamaoka, Yasuyo; Inatsugi, Rie; Fujiki, Yuki; Oikawa, Akira; Saito, Kazuki; Nishida, Ikuo: Epigenetic floral homeotic mutation in pD991-AP3-derived T-DNA-tagged lines for CTP:Phosphorylcholine cytidylyltransferase (CCT) Genes: The homeotic mutation of the cct1-1 allele is enhanced by the cct2 allele and alleviated by CCT1 overexpression. JOURNAL OF PLANT BIOLOGY, 58, 183-192 (2015)
  15. Higashi, Yasuhiro; Okazaki, Yozo; Myouga, Fumiyoshi; Shinozaki, Kazuo; Saito, Kazuki: Landscape of the lipidome and transcriptome under heat stress in Arabidopsis thaliana. SCIENTIFIC REPORTS, 5, 10533 (2015)
  16. Di, Shaokang; Yan, Fan; Rodas, Felipe Rojas; Rodriguez, Tito O.; Murai, Yoshinori; Iwashina, Tsukasa; Sugawara, Satoko; Mori, Tetsuya; Nakabayashi, Ryo; Yonekura-Sakakibara, Keiko; Saito, Kazuki; Takahashi, Ryoji: Linkage mapping, molecular cloning and functional analysis of soybean gene Fg3 encoding flavonol 3-O-glucoside/galactoside (1 -> 2) glucosyltransferase. BMC PLANT BIOLOGY, 15, 26 (2015)
  17. Suzuki, Mami; Nakabayashi, Ryo; Ogata, Yoshiyuki; Sakurai, Nozomu; Tokimatsu, Toshiaki; Goto, Susumu; Suzuki, Makoto; Jasinski, Michal; Martinoia, Enrico; Otagaki, Shungo; Matsumoto, Shogo; Saito, Kazuki; Shiratake, Katsuhiro: Multiomics in Grape Berry Skin Revealed Specific Induction of the Stilbene Synthetic Pathway by Ultraviolet-C Irradiation. PLANT PHYSIOLOGY, 168, 47-59 (2015)
  18. Sirikantaramas, Supaart; Meeprasert, Arthitaya; Rungrotmongkol, Thanyada; Fuji, Hideyoshi; Hoshino, Tyuji; Sudo, Hiroshi; Yamazaki, Mami; Saito, Kazuki: Structural insight of DNA topoisomerases I from camptothecin-producing plants revealed by molecular dynamics simulations. PHYTOCHEMISTRY, 113, 50-56 (2015)
  19. Nakabayashi, Ryo; Yang, Zhigang; Nishizawa, Tomoko; Mori, Tetsuya; Saito, Kazuki: Top-down Targeted Metabolomics Reveals a Sulfur-Containing Metabolite with Inhibitory Activity against Angiotensin-Converting Enzyme in Asparagus officinalis. JOURNAL OF NATURAL PRODUCTS, 78, 1179-1183 (2015)
  20. Maruyama-Nakashita, Akiko; Watanabe-Takahashi, Akiko; Inoue, Eri; Yamaya, Tomoyuki; Saito, Kazuki; Takahashi, Hideki: Sulfur-Responsive Elements in the 3 '-Nontranscribed Intergenic Region Are Essential for the Induction of SULFATE TRANSPORTER 2;1 Gene Expression in Arabidopsis Roots under Sulfur Deficiency. PLANT CELL, 27, 1279-1296 (2015)
  21. Nakabayashi, Ryo; Saito, Kazuki: Integrated metabolomics for abiotic stress responses in plants. CURRENT OPINION IN PLANT BIOLOGY 24, 10-16 (2015)
  22. Kusano, Miyako; Baxter, Ivan; Fukushima, Atsushi; Oikawa, Akira; Okazaki, Yozo; Nakabayashi, Ryo; Bouvrette, Denise J.; Achard, Frederic; Jakubowski, Andrew R.; Ballam, Joan M.; Phillips, Jonathan R.; Culler, Angela H.; Saito, Kazuki; Harrigan, George G.: Assessing metabolomic and chemical diversity of a soybean lineage representing 35 years of breeding. METABOLOMICS, 11, 261-270 (2015)
  23. Imashimizu, Masahiko; Takahashi, Hiroki; Oshima, Taku; McIntosh, Carl; Bubunenko, Mikhail; Court, Donald L.; Kashlev, Mikhail: Visualizing translocation dynamics and nascent transcript errors in paused RNA polymerases in vivo. GENOME BIOLOGY, 16, 98 (2015)
  24. Takahashi, Hiroki; Oshima, Taku; Hobman, Jon L.; Doherty, Neil; Clayton, Selina R.; Iqbal, Mudassar; Hill, Philip J.; Tobe, Toru; Ogasawara, Naotake; Kanaya, Shigehiko; Stekel, Dov J.: The dynamic balance of import and export of zinc in Escherichia coli suggests a heterogeneous population response to stress. JOURNAL OF THE ROYAL SOCIETY INTERFACE, 12, UNSP 20150069 (2015)
  25. Takahashi-Nakaguchi, Azusa; Muraosa, Yasunori; Hagiwara, Daisuke; Sakai, Kanae; Toyotome, Takahito; Watanabe, Akira; Kawamoto, Susumu; Kamei, Katsuhiko; Gonoi, Tohru; Takahashi, Hiroki: Genome sequence comparison of Aspergillus fumigatus strains isolated from patients with pulmonary aspergilloma and chronic necrotizing pulmonary aspergillosis. MEDICAL MYCOLOGY, 53, 353-360 (2015)
  26. Sato, Masaru; Sakurai, Nozomu; Suzuki, Hideyuki; Shibata, Daisuke; Kino, Kuniki: Enzymatic carboxylation of hydroxystilbenes by the gamma-resorcylic acid decarboxylase from Rhizobium radiobacter WU-0108 under reverse reaction conditions. JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC, 122, 348-352 (2015)
  27. Mizuno, Shinji; Sonoda, Masatoshi; Tamura, Yayoi; Nishino, Eisho; Suzuki, Hideyuki; Sato, Takahide; Oizumi, Toshikatsu: Chiba Tendril-Less locus determines tendril organ identity in melon (Cucumis melo L.) and potentially encodes a tendril-specific TCP homolog. JOURNAL OF PLANT RESEARCH, 128, 941-951 (2015)
  28. Takahashi, Haruya; Kamakari, Kosuke; Goto, Tsuyoshi; Hara, Hideyuki; Mohri, Shinsuke; Suzuki, Hideyuki; Shibata, Daisuke; Nakata, Rieko; Inoue, Hiroyasu; Takahashi, Nobuyuki; Kawada, Teruo: 9-Oxo-10(E),12(Z),15(Z)-Octadecatrienoic Acid Activates Peroxisome Proliferator-Activated Receptor alpha in Hepatocytes. LIPIDS, 50, 1083-1091 (2015)
  29. Hirose, Yoshitsugu; Suda, Kunihiro; Liu, Yao-Guang; Sato, Shusei; Nakamura, Yukino; Yokoyama, Koji; Yamamoto, Naoki; Hanano, Shigeru; Takita, Eiji; Sakurai, Nozomu; Suzuki, Hideyuki; Nakamura, Yasukazu; Kaneko, Takakazu; Yano, Kentaro; Tabata, Satoshi; Shibata, Daisuke: The Arabidopsis TAC Position Viewer: a high-resolution map of transformation-competent artificial chromosome (TAC) clones aligned with the Arabidopsis thaliana Columbia-0 genome. PLANT JOURNAL, 83, 1114-1122 (2015)
  30. Nakamura, Noriko; Katsumoto, Yukihisa; Brugliera, Filippa; Demelis, Linda; Nakajima, Daisuke; Suzuki, Hideyuki; Tanaka, Yoshikazu: Flower color modification in Rosa hybrida by expressing the S-adenosylmethionine: anthocyanin 3 ',5 '-O-methyltransferase gene from Torenia hybrida. PLANT BIOTECHNOLOGY, 32, 109-117 (2015)
  31. Liu, Chengwei; Tagami, Koichi; Minami, Atsushi; Matsumoto, Tomoyuki; Frisvad, Jens Christian; Suzuki, Hideyuki; Ishikawa, Jun; Gomi, Katsuya; Oikawa, Hideaki: Reconstitution of Biosynthetic Machinery for the Synthesis of the Highly Elaborated Indole Diterpene Penitrem. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 54, 5748-5752 (2015)
  32. Li, Donghan; Ono, Naoaki; Sato, Tetsuo; Sugiura, Tadao; Altaf-Ul-Amin, Md; Ohta, Daisaku; Suzuki, Hideyuki; Arita, Masanori; Tanaka, Ken; Ma, Zhiqiang; Kanaya, Shigehiko: Targeted Integration of RNA-Seq and Metabolite Data to Elucidate Curcuminoid Biosynthesis in Four Curcuma Species. PLANT AND CELL PHYSIOLOGY, 56, 843-851 (2015)
  33. Kusuda, Hiroki; Koga, Wataru; Kusano, Miyako; Oikawa, Akira; Saito, Kazuki; Hirai, Masami Yokota; Yoshida, Kaoru T.: Ectopic expression of myo-inositol 3-phosphate synthase induces a wide range of metabolic changes and confers salt tolerance in rice. PLANT SCIENCE, 232, 49-56 (2015)
  34. Speiser, Anna; Haberland, Stefan; Watanabe, Mutsumi; Wirtz, Markus; Dietz, Karl-Josef; Saito, Kazuki; Hell, Ruediger: The significance of cysteine synthesis for acclimation to high light conditions. FRONTIERS IN PLANT SCIENCE, 5, 776 (2015)
  35. Yoshimoto, Naoko; Yabe, Ayami; Sugino, Yuka; Murakami, Soichiro; Sai-ngam, Niti; Sumi, Shin-ichiro; Tsuneyoshi, Tadamitsu; Saito, Kazuki: Garlic gamma-glutamyl transpeptidases that catalyze deglutamylation of biosynthetic intermediate of alliin. FRONTIERS IN PLANT SCIENCE, 5, 758 (2015)
  36. Kusano, Miyako; Yang, Zhigang; Okazaki, Yozo; Nakabayashi, Ryo; Fukushima, Atsushi; Saito, Kazuki: Using Metabolomic Approaches to Explore Chemical Diversity in Rice. MOLECULAR PLANT, 8, 58-67 (2015)
  37. Bohrer, Anne-Sophie; Yoshimoto, Naoko; Sekiguchi, Ai; Rykulski, Nicholas; Saito, Kazuki; Takahashi, Hideki: Alternative translational initiation of ATP sulfurylase underlying dual localization of sulfate assimilation pathways in plastids and cytosol in Arabidopsis thaliana. FRONTIERS IN PLANT SCIENCE, 5, 750 (2015)
  38. Sumner, Lloyd W.; Lei, Zhentian; Nikolau, Basil J.; Saito, Kazuki: Modern plant metabolomics: advanced natural product gene discoveries, improved technologies, and future prospects. NATURAL PRODUCT REPORTS, 32, 212-229 (2015)
  39. Matsuda, Fumio; Nakabayashi, Ryo; Yang, Zhigang; Okazaki, Yozo; Yonemaru, Jun-ichi; Ebana, Kaworu; Yano, Masahiro; Saito, Kazuki: Metabolome-genome-wide association study dissects genetic architecture for generating natural variation in rice secondary metabolism. PLANT JOURNAL, 81, 13-23 (2015)
  40. Tanimoto, Jun; Fujino, Hiromichi; Takahashi, Hiroki; Murayama, Toshihiko: Human EP2 prostanoid receptors exhibit more constraints to mutations than human DP prostanoid receptors. FEBS LETTERS, 589, 766-772 (2015)
  41. Takahashi, Haruya; Goto, Tsuyoshi; Yamazaki, Yota; Kamakari, Kosuke; Hirata, Mariko; Suzuki, Hideyuki; Shibata, Daisuke; Nakata, Rieko; Inoue, Hiroyasu; Takahashi, Nobuyuki; Kawada, Teruo: Metabolomics reveal 1-palmitoyl lysophosphatidylcholine production by peroxisome proliferator-activated receptor alpha. JOURNAL OF LIPID RESEARCH, 56, 254-265 (2015)
  42. Takahashi, Haruya; Hara, Hideyuki; Goto, Tsuyoshi; Kamakari, Kosuke; Wataru, Nomura; Mohri, Shinsuke; Takahashi, Nobuyuki; Suzuki, Hideyuki; Shibata, Daisuke; Kawada, Teruo: 13-Oxo-9(Z),11(E),15(Z)-octadecatrienoic Acid Activates Peroxisome Proliferator-Activated Receptor gamma in Adipocytes. LIPIDS, 50, 3-12 (2015)
  43. Yixizhuoma; Tsukahara, Kentaro; Toume, Kazufumi; Ishikawa, Naoki; Abdelfattah, Mohamed S.; Ishibashi, Masami: Novel cytotoxic isobenzofuran derivatives from Streptomyces sp IFM 11490. TETRAHEDRON LETTERS, 56, 6345-6347 (2015)
  44. Arai, Midori A.; Akamine, Ryuta; Sadhu, Samir K.; Ahmed, Firoj; Ishibashi, Masami: Hedgehog/GLI-mediated transcriptional activity inhibitors from Crinum asiaticum. JOURNAL OF NATURAL MEDICINES, 69, 538-542 (2015)
  45. Fuentes, Rolly G.; Arai, Midori A.; Sadhu, Samir K.; Ahmed, Firoj; Ishibashi, Masami: Phenolic compounds from the bark of Oroxylum indicum activate the Ngn2 promoter. JOURNAL OF NATURAL MEDICINES, 69, 589-594 (2015)
  46. Ohishi, Kensuke; Toume, Kazufumi; Arai, Midori A.; Sadhu, Samir K.; Ahmed, Firoj; Ishibashi, Masami: Coronaridine, an iboga type alkaloid from Tabernaemontana divaricata, inhibits the Wnt signaling pathway by decreasing beta-catenin mRNA expression. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 25, 3937-3940 (2015)
  47. Yoneyama, Tatsuro; Arai, Midori A.; Sadhu, Samir K.; Ahmed, Firoj; Ishibashi, Masami: Hedgehog inhibitors from Withania somnifera. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 25, 3541-3544 (2015)
  48. Arai, Midori A.; Uchida, Kyoko; Sadhu, Samir K.; Ahmed, Firoj; Koyano, Takashi; Kowithayakorn, Thaworn; Ishibashi, Masami: Hedgehog inhibitors from Artocarpus communis and Hyptis suaveolens. BIOORGANIC & MEDICINAL CHEMISTRY, 23, 4150-4154 (2015)
  49. Karmakar, Utpal K.; Ishikawa, Naoki; Toume, Kazufumi; Arai, Midori A.; Sadhu, Samir K.; Ahmed, Firoj; Ishibashi, Masami: Sesquiterpenes with TRAIL-resistance overcoming activity from Xanthium strumarium. BIOORGANIC & MEDICINAL CHEMISTRY, 23, 4746-4754 (2015)
  50. Shono, Takumi; Ishikawa, Naoki; Toume, Kazufumi; Arai, Midori A.; Ahmed, Firoj; Sadhu, Samir K.; Ishibashi, Masami: Boehmenan, a lignan from Hibiscus ficulneus, showed Wnt signal inhibitory activity. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 25, 2735-2738 (2015)
  51. Ohishi, Kensuke; Toume, Kazufumi; Arai, Midori A.; Koyano, Takashi; Kowithayakorn, Thaworn; Mizoguchi, Takamasa; Itoh, Motoyuki; Ishibashi, Masami: 9-Hydroxycanthin-6-one, a beta-Carboline Alkaloid from Eurycoma longifolia, Is the First Wnt Signal Inhibitor through Activation of Glycogen Synthase Kinase 3 beta without Depending on Casein Kinase 1 alpha. JOURNAL OF NATURAL PRODUCTS, 78, 1139-1146 (2015)
  52. Fuentes, Rolly G.; Toume, Kazufumi; Arai, Midori A.; Sadhu, Samir K.; Ahmed, Firoj; Ishibashi, Masami: Scopadulciol, Isolated from Scoparia dulcis, Induces beta-Catenin Degradation and Overcomes Tumor Necrosis Factor-Related Apoptosis Ligand Resistance in AGS Human Gastric Adenocarcinoma Cells. JOURNAL OF NATURAL PRODUCTS, 78, 864-872 (2015)
  53. Kagawa, Natsuko; Suzuki, Masaaki; Kogure, Noriyuki; Toume, Kazufumi: Characterization of organic iodides with iodine-127 nuclear magnetic resonance spectroscopy. TETRAHEDRON LETTERS, 56, 5795-5798 (2015)
  54. Ishida, Hiroaki; Kimura, Shinya; Kogure, Noriyuki; Kitajima, Mariko; Takayama, Hiromitsu: Total synthesis of (+/-)-lycoposerramine-R, a novel skeletal type of Lycopodium alkaloid. TETRAHEDRON, 71, 51-56 (2015)
  55. Saidin, Nor Aini; Holmes, Elaine; Takayama, Hiromitsu; Gooderham, Nigel J.: The cellular toxicology of mitragynine, the dominant alkaloid of the narcotic-like herb, Mitragyna speciosa Korth. TOXICOLOGY RESEARCH, 4, 1173-1183 (2015)
  56. Ishida, Hiroaki; Kimura, Shinya; Kogure, Noriyuki; Kitajima, Mariko; Takayama, Hiromitsu: The first asymmetric total synthesis of lycoposerramine-R. ORGANIC & BIOMOLECULAR CHEMISTRY, 13, 7762-7771 (2015)
  57. Kitajima, Mariko; Koyama, Tetsuya; Wu, Yuqiu; Kogure, Noriyuki; Zhang, Rongping; Takayama, Hiromitsu: Kopsiyunnanines J1 and J2, New Strychnos-type Homo-Monoterpenoid Indole Alkaloids from Kopsia arborea. NATURAL PRODUCT COMMUNICATIONS, 10, 49-51 (2015)
  58. Fuentes, Rolly G.; Toume, Kazufumi; Arai, Midori A.; Sadhu, Samir K.; Ahmed, Firoj; Ishibashi, Masami: Limonoids with Wnt signal inhibitory activity isolated from the fruits of Azadirachta excels. PHYTOCHEMISTRY LETTERS, 11, 280-285 (2015)
  59. Arai, Midori A.; Koryudzu, Kazune; Ishibashi, Masami: Inubosins A, B, and C Are Acridine Alkaloids Isolated from a Culture of Streptomyces sp IFM 11440 with Ngn2 Promoter Activity. JOURNAL OF NATURAL PRODUCTS, 78, 311-314 (2015)
  60. Fuentes, Rolly G.; Arai, Midori A.; Ishibashi, Masami: Natural compounds with Wnt signal modulating activity. NATURAL PRODUCT REPORTS 32, 1622-1628 (2015)
  61. Arai, Midori A.; Uemura, Kenji; Hamahiga, Nozomi; Ishikawa, Naoki; Koyano, Takashi; Kowithayakorn, Thaworn; Kaddar, Tagrid; Carreau, Madeleine; Ishibashi, Masami: Naturally occurring FANCF-Hes1 complex inhibitors from Wrightia religiosa. MEDCHEMCOMM, 6, 455-460 (2015)
  62. Tahmina, Hogue; Toume, Kazufumi; Arai, Midori A.; Sadhu, Samir K.; Ahmed, Firoj; Ishibashi, Masami: ISOLATION OF ALKAMIDES WITH DEATH RECEPTOR-ENHANCING ACTIVITIES FROM PIPER CHABA. HETEROCYCLES, 90, 1317-1322 (2015)
  63. Toume, Kazufumi; Habu, Tadashi; Arai, Midori A.; Koyano, Takashi; Kowithayakorn, Thaworn; Ishibashi, Masami: Prenylated Flavonoids and Resveratrol Derivatives Isolated from Artocarpus communis with the Ability to Overcome TRAIL Resistance. JOURNAL OF NATURAL PRODUCTS, 78, 103-110 (2015)
  64. Niimi, Hiroyuki; Watanabe, Masami; Serizawa, Hiroaki; Koba, Takato; Nakamura, Ikuo; Mii, Masahiro: Amiprophosmethyl-induced efficient in vitro production of polyploids in raphanobrassica with the aid of aminoethoxyvinylglycine (AVG) in the culture medium. BREEDING SCIENCE, 65, 396-402 (2015)
  65. Mori, Toshiyuki; Kawai-Toyooka, Hiroko; Igawa, Tomoko; Nozaki, Hisayoshi: Gamete Dialogs in Green Lineages. MOLECULAR PLANT, 8, 1442-1454 (2015)
  66. Maruyama, Daisuke; Voelz, Ronny; Takeuchi, Hidenori; Mori, Toshiyuki; Igawa, Tomoko; Kurihara, Daisuke; Kawashima, Tomokazu; Ueda, Minako; Ito, Masaki; Umeda, Masaaki; Nishikawa, Shuh-ichi; Gross-Hardt, Rita; Higashiyama, Tetsuya: Rapid Elimination of the Persistent Synergid through a Cell Fusion Mechanism. CELL, 161, 907-918 (2015)
  67. Ntui, Valentine Otang; Kong, Kynet; Khan, Raham Sher; Igawa, Tomoko; Janavi, Gnanaguru Janaky; Rabindran, Ramalingam; Nakamura, Ikuo; Mii, Masahiro: Resistance to Sri Lankan Cassava Mosaic Virus (SLCMV) in Genetically Engineered Cassava cv. KU50 through RNA Silencing. PLOS ONE, 10, e0120551 (2015)
  68. Fujii, Gaku; Imamura, Sousuke; Era, Atsuko; Miyagishima, Shin-ya; Hanaoka, Mitsumasa; Tanaka, Kan: The nuclear-encoded sigma factor SIG4 directly activates transcription of chloroplast psbA and ycf17 genes in the unicellular red alga Cyanidioschyzon merolae. FEMS MICROBIOLOGY LETTERS, 362, fnv063 (2015)
  69. Lu, Na; Nukaya, Tsunaki; Kamimura, Taichi; Zhang, Dalong; Kurimoto, Ikusaburo; Takagaki, Michiko; Maruo, Toru; Kozai, Toyoki; Yamori, Wataru: Control of vapor pressure deficit (VPD) in greenhouse enhanced tomato growth and productivity during the winter season. SCIENTIA HORTICULTURAE, 197, 17-23 (2015)
  70. Yamori, Wataru; Shikanai, Toshiharu; Makino, Amane: Photosystem I cyclic electron flow via chloroplast NADH dehydrogenase-like complex performs a physiological role for photosynthesis at low light. SCIENTIFIC REPORTS, 5, 13908 (2015)
  71. Noguchi, Ko; Yamori, Wataru; Hikosaka, Kouki; Terashima, Ichiro: Homeostasis of the temperature sensitivity of respiration over a range of growth temperatures indicated by a modified Arrhenius model. NEW PHYTOLOGIST, 207, 34-42 (2015)
  72. Hamano, Mizuna; Akimoto, Mayuko; Funada, Keiko; Kagawa, Natsuko; Suzuki, Noriyuki; Ishikawa, Tsutomu: Construction of a Bicyclo[3.2.1]octane System Carrying the (R)-Carvone Core under Oxidative Radical Conditions: Synthetic Access to (+)-Miroestrols. SYNLETT, 26, 547-551 (2015)

2. 総説・出版

2016

  1. 山崎真巳:薬用植物のファイトケミカルゲノミクス.和漢薬,756, 2 (2016)
  2. Arthur S. Edison, Robert D. Hall, Christophe Junot, Peter D. Karp, Irwin J. Kurland, Robert Mistrik, Laura K. Reed, Kazuki Saito, Reza M. Salek, Christoph Steinbeck, Lloyd W. Sumner and Mark R. Viant. The Time Is Right to Focus on Model Organism Metabolomes. Metabolites, 6, 8; doi:10.3390/metabo6010008 (2016)
  3. Amit Rai, and Kazuki Saito: Omics data input for metabolic modeling. Curr. Opin. Biotech., 37, 127–134 (2016)
  4. Yozo Okazaki and Kazuki Saito: Integrated metabolomics and phytochemical genomics approaches for studies on rice. GigaScience, 5:11, DOI: 10.1186/s13742-016-0116-7 (2016)
  5. Ryo Nakabayashi and Kazuki Saito: Ultrahigh resolution metabolomics for S-containing metabolites. Curr. Opin. Biotech., in press (2016)
  6. Kitajima, M., and Takayama, H.: Monoterpenoid bisindole alkaloids. “The Alkaloids: Chemistry and Biology”, ed. by Knölker, H.-J., Academic Press, Vol. 76, p. 259-309, (2016)
  7. 高山廣光: 天然物の生合成に関する知見•考察をアルカロイド全合成に活かす, 徳島大学創薬先端合成化学セミナー (2016)
  8. 高山廣光: 生物活性アルカロイドの探索と精密構造解析, 理研シンポジウム: 高磁場•高感度NMR利活用促進のための天然物関連シンポジウム2016 (2016)
  9. Abdelfattah, M. S., Arai, M. A., and Ishibashi, M.: Bioactive secondary metabolites with unique aromatic and heterocyclic structures obtained from terrestrial actinomycetes species. Chem. Pharm. Bull. 64, 668-675 (2016)
  10. Ishibashi, M.: Foreward of special section celebrating Professor Satosi Omura’s 2015 Nobel Prize in Physiology or Medicine. Chem. Pharm. Bull. 64, 655 (2016)
  11. 石橋正己: がんの進展に関わる細胞シグナルを標的とした天然物の探索,FFIジャーナル,221, 94-99 (2016)
  12. 石橋正己: ご受賞を祝して(大村智博士ノーベル賞受賞記念特集),化学と生物,54, 67 (2016)
  13. Ahmed, F., and Ishibashi, M.: Bio-active natural products with TRAIL-resistance overcoming activity. Chem. Pharm. Bull. 64, 119-127 (2016)
  14. Yamori, W., Shikanai, T.: Physiological Functions of Cyclic Electron Transport Around Photosystem I in Sustaining Photosynthesis and Plant Growth. Annual Review of Plant Biology 67:81–106 (2016)
  15. Yamori, W.: Photosynthetic response to fluctuating environments and photoprotective strategies under abiotic stress. Journal of Plant Research 129:379–395 (2016)
  16. Yamori, W., Irving, L.J., Adachi, S. Busch, F.A.: Strategies for optimizing photosynthesis with biotechnology to improve crop yield. In Handbook of Photosynthesis, 3rd Edition. CRC Press. 741-760 (2016)
  17. Brandon, M.F., Lu, N., Yamaguchi, T., Takagaki, M., Maruo, T., Kozai, T., Yamori, W.: The Next Evolution of Agriculture: A review of innovations in Plant Factories. In Handbook of Photosynthesis, 3rd Edition. CRC Press. pp723-740 (2016)
  18. Yamori, W. Photosynthesis and respiration. In Plant Factory: An Indoor Vertical Farming System for Efficient Quality Food Production, Elsevier. pp141-150 (2016)

2015

  1. 斉藤和季、“植物由来天然物の生合成とエンジニアリング” 第二次先端ウオッチング調査:融合領域の創成 天然物化学研究の最前線:生合成とケミカルバイオロジーの新展開、日本化学会 pp.39 (2015)
  2. 斉藤和季(分担執筆)“大学院講義 有機化学 第2版 II.有機合成化学・生物有機化学”野依良治 編集代表、東京化学同人 (2015)
  3. 高山廣光:生薬の化学成分:アルカロイド. 漢方薬・生薬薬剤師講座テキスト 4, pp. 142-154, 公益財団法人 日本薬剤師研修センター (2015)
  4. 高山廣光:アルカロイドに見る有機合成化学の力量. 有機合成化学協会誌, 73 (3), 219 (2915)
  5. Kitajima, M., and Takayama, H.: Chemistry of Mitragyna alkaloids. Chapter 8 (p. 101-116), “Kratom and Other Mitragynines: The Chemistry and Pharmacology of Opioids from a Non-Opium Source”, ed. by Raffa, R. B., CRC Press (2015)
  6. Takayama, H., and Kitajima, M.: Medicinal chemistry based on mitragynine. Chapter 9 (p. 117-134), “Kratom and Other Mitragynines: The Chemistry and Pharmacology of Opioids from a Non-Opium Source”, ed. by Raffa, R. B., CRC Press (2015)
  7. 北島満里子, 寺田祐子, 渡辺達夫, 堀江俊治, 高山廣光: 温度感受性TRPチャネルアンタゴニスト活性を有するVoacangine型アルカロイドの探索・合成と構造活性相関研究. MEDCHEM NEWS, 25 (3), 132-137 (2015)
  8. Takayama, H.: Recent Progress in Total Synthesis of Lycopodium Alkaloids. J. Synth. Org. Chem. Jpn., 73 (11), 1062-1071 (2015)
  9. 寺田祐子, 堀江俊治, 北島満里子, 高山廣光, 渡辺達夫:Voacanga africana由来アルカロイドvoacangineの温度感受性TRPチャネルに対する活性・阻害作用. 食品加工技術 (日本食品・機械研究会誌), 35 (2), 1-12 (49-60) (2015)
  10. Kitajima, M., and Takayama, H.: Chemistry of Mitragyna alkaloids. Chapter 8 (p. 101-116), “Kratom and Other Mitragynines: The Chemistry and Pharmacology of Opioids from a Non-Opium Source”, ed. by Raffa, R. B., CRC Press (2015)
  11. 石橋正己:膜脂質と脂肪酸誘導体.大学院講義有機化学Ⅱ 第2版,野依良治・中筋一弘・玉尾皓平・奈良坂紘一・柴﨑正勝・橋本俊一・鈴木啓介・山本陽介・村田道雄編,pp. 377-382, 東京化学同人 (2015)
  12. 野依良治,奥山格,柴﨑正勝,檜山為次郎(監訳),石橋正己,岩澤伸治,大嶋孝志,金井求,木越英夫,忍久保洋,白川英二,橋本俊一,吉田潤一(共訳):ウォーレン有機化学 第2版(上)(下),東京化学同人 (2015)

3. 招待講演

2016

  1. Saito, K.: Phytochemical Genomics for Identification of Genes Involved in Biosynthesis of Specialized Products in Medicinal Plants. The 9th CSP-KSP-JSP Joint Symposium on Pharmacognosy & 2016 Annial Conference of Committee of Chinese Traditional and Natural Medicines, Chinese Pharmaceutical Association. Shanghai, Chinese (2016)
  2. Yamazaki, M.: Gene discovery for specialized metabolisms by genomics, transcriptomics and metabolomics. Plant Biology Europe EPSO/FESPB 2016 Congress. Prague, Czech Republic (2016)
  3. 山崎真巳:植物のアルカロイド生合成機構から学ぶこと,第51回天然物化学談話会,新潟 (2016)
  4. K. Saito: Phytochemical genomics – from a model plant to medicinal plants. 9th Joint Natural Procucts Conference 2016. Copenhagen, Denmark. July 24-27, 2016.
  5. H. Takayama: Bioinspired Syntheses of Alkaloids Isolated from Medicinal Plants, The 9th CSP-KSP-JSP Joint Symposium on Pharmacognosy & 2016 Annual Conference of Committee of Chinese Traditional and Natural Medicines, Chinese Pharmaceutical Association (2016)
  6. 小暮紀行:コプシア属植物含有生物活性アルカロイドの探索と化学的研究. 第21回 天然薬物の開発と応用シンポジウム(2016)
  7. 荒井緑:天然物を基盤とした生物活性分子の探索と創製,JSPS第189委員会 日本におけるケミカルバイオロジーの新展開(2016)
  8. 石橋正己:変形菌成分フリゴキャンジンBの標的解析,新学術領域研究「天然物ケミカルバイオロジー」研究成果報告シンポジウム,慶應義塾大学 (2016)
  9. Ishibashi M.: Screening studies for natural products on disease and development pathways, International Symposium on Natural Products for the Future 2016 TOKUSHIMA (2016)
  10. 荒井緑:神経再生とがんの制御をめざした天然物基盤分子の創成研究,第21回 天然薬物の開発と応用シンポジウム(2016)
  11. 荒井緑:天然物を基盤とした生物活性分子の探索と創製,横浜市立大学教室セミナー(2016)
  12. Ishibashi M.: Search for bioactive constituents having effects on disease and development pathways from medicinal plants in Thailand, Herbal Traditional Medicine Symposium (HTM 2017) , Bangkok, (2017)
  13. Eiji Goto. Technology development and commercialization of high value added plant production in plant factory. The International Symposium on Commercialization of Smart Farm (GARES Symposium), (May 12, 2016). Gyeonggi-do, Korea.
  14. 後藤英司. 植物工場の最先端-すぐそこにある未来の野菜作りとは?. CIAJフォーラムプラザシンポジウム2016(一般社団法人情報通信ネットワーク産業協会)、2016年7月. 港区
  15. 後藤英司. 人工光型植物工場の最新動向. 施設園芸・植物工場展2016特別セミナー(日本施設園芸協会). 2016年7月. 江東区

2015

  1. Saito, K.: Plant Metabolomics - Potential and Reality, Korea Metabolomics Society. 2015 Annual Symposium and General Meeting. Metabolomics from the Convergence of Chemistry and Biology, Busan, Korea (2015)
  2. Saito, K.: Integration of metabolomics with genomics and transcriptomics for gene discovery in plants, The 20th Penn State Plant Biology Symposium. Plant Stress-Omics in a Changing Climate, University Park, PA, US (2015)
  3. Saito, K.: Metabolomics and origin of chemical diversity in plants., Cluster of Excellence on Plant Sciences (CEPLAS) Symposium, Cologne, Germany (2015)
  4. 斉藤和季:ゲノム,メタボローム解析情報に基づく二次代謝産物設計図の解読,新学術領域研究「生合成マシナリー」成果報告シンポジウム,東京 (2015)
  5. Saito, K.: Combining metabolomics with genomics: From Arabidopsis to crops and medicinal plants, Gordon Research Conference, Plant Metabolic Engineering, Waterville Valley, NH, USA (2015)
  6. Yoshimoto, N., and Saito, K.: Biosynthesis of sulfur-containing secondary metabolites in garlic, 10th Jubilee Plant Sulfur Workshop, Goslar, Germany (2015)
  7. Saito, K.: Discovery of novel genes and metabolites by integration of metabolomics and genomics, 11th International Congress of Plant Molecular Biology IPMB 2015 South America, Iguassu Falls, Brazil (2015)
  8. Yamazaki, M., Bunsupa, S., and Saito, K.: The origin of biosynthesis of lysine-derived alkaloids, 11th International Congress of Plant Molecular Biology IPMB 2015 South America, Iguassu Falls, Brazil (2015)Saito, K.: Biosynthetic study of plant specialized products by means of genomics and metabolomics, The International Chemical Congress of Pacific Basin Societies 2015, Honolulu, Hawaii, USA (2015)
  9. Yamazaki, M., Bunsupa, S., and Saito, K.: Evolution of lysine-derived alkaloid biosynthesis, The International Chemical Congress of Pacific Basin Societies 2015, Honolulu, Hawaii, USA (2015)
  10. 斉藤和季:ゲノム、メタボローム解析情報に基づく二次台代謝産物設計図の解読.文部科学省科学研究費補助金 新学術領域研究 「生合成マシナリー」成果報告シンポジウム.(平成27年6月21日.東京)
  11. 吉本尚子:植物での硫黄の輸送、代謝と含硫黄成分の生合成に関する分子生物学的研究,第6回食品薬学シンポジウム,岡山 (2015)
  12. 斉藤和季:現状の概観と薬用資源植物のゲノム機能科学.日本学術会議 薬学委員会 生物系薬学分科会 化学・物理系薬学分科会 日本薬学会シンポジウム 「生薬の安定供給と開発に向けた薬用資源科学」(平成28年1月8日.東京)
  13. 斉藤和季:植物メタボロミクスの開発とゲノム機能科学研究への応用.第57回日本植物生理学会年会,盛岡 (2016)
  14. Mami Yamazaki: Cellular dynamics of lysine derived alkaloids in plants. 第57回日本植物生理学会年会,S06-6.(平成28年3月18-20日.盛岡)
  15. 吉本尚子:ニンニクの含硫黄薬理成分アリインの生合成機構の解析と酵素遺伝子の同定。第4回植物二次代謝フロンティア研究会例会,花巻 (2016)
  16. 高山廣光:生物活性アルカロイドの探索・合成・創薬化学研究, 日本生薬学会第62回年会, 岐阜 (2015)
  17. 北島満里子:温度感受性TRPチャネルアンタゴニスト活性を有するVoacangine 関連化合物の全合成研究と構造活性相関. 第33回メディシナルケミストリーシンポジウム, 千葉 (2015)
  18. 高山廣光:生物活性アルカロイドの探索と合成 –創薬研究に向けて–, 慶應義塾大学大学院薬学研究科セミナー, 東京 (2015)
  19. 石橋正己:ウィントシグナル阻害作用をもつ天然物のスクリーニング, 天然有機化合物の生合成研究―新潟ミニシンポジウム―,新潟 (2015)
  20. 荒井緑:神経幹細胞分化活性化を目指した天然基盤分子の探索,新学術領域研究「天然物ケミカルバイオロジー~分子標的と活性制御~」地区ミニシンポジウム・仙台「ケミカルバイオロジーにおける天然物」,仙台 (2015)
  21. 石橋正己:シグナル伝達調節作用をもつテルぺノイド成分の探索, 第59回香料・テルペンおよび精油化学に関する討論会,大阪 (2015)
  22. Ishibashi, M.: Natural products-based screening study on disease and development pathways, Pacifichem 2015; Honolulu, USA (2015)
  23. Arai, M. A.: Search for neural stem cell activators based on natural products", Asian Chemical Biology Initiative 2016 Jakarta Meeting, Jakarta (2016)
  24. 後藤英司. 遺伝子組換え植物工場を用いた医薬品原材料の生産.日本化学会春季大会ATP. 2015年4月. 船橋市
  25. 後藤英司. 植物工場の最新動向と今後の展望. 山口県産業技術センター平成27年度第1回次世代エネルギー研究会. 2015年4月.山口市
  26. Eiji Goto. Production of pharmaceuticals in a specially designed plant factory. The International Congress on Controlled Environment Agriculture. Panama on 22 May, 2015
  27. Eiji Goto. Plant Factories and Control of Plant Growth under Artificial Light. 2015年植物工場技術に関する公開講座第4回. 中国農業大学. 2015年6月. 北京、中国
  28. 後藤英司. 植物工場-工業と農業の融合による最先端の生物生産システム-. プリンテッドエレクトロニクス研究会. 2015年7月. 港区
  29. 後藤英司. 人工光型植物工場標準仕様書の解説 ~よりよい施設づくりと安定生産を目指して~. 人工光型植物工場協議会セミナー. 2015年10月. 柏市
  30. 後藤英司. 施設園芸・植物工場における機能性農産物の新展開. アグロ・イノベーション2015セミナー. 2015年11月. 江東区
  31. Eiji Goto. Modeling of tomato growth and prediction of yield of tomato under various environmental conditions in greenhouses. Dankook University Seminar. (December 9, 2015), Dankook University, Gyeonggi-do, Korea.
  32. E. Goto, Y. Ohashi, T. Furuya, A. Marumi and Y. Saito. Environmental control for high value added plant production in a greenhouse and a plant factory. Joint-Workshop for Plant Factory. December 21, 2015, Seoul, Korea
  33. Eiji Goto. Climate: Environmental Controls (Light, Temp, Humidity, CO2, Air current). Indoor Ag-Con Asia. (January 18, 2016), Singapore
  34. 後藤英司. 施設園芸の環境制御への取り組み. 熊本施設園芸環境制御高度化協議会・施設園芸の高度環境制御技術研修会. 2016年2月. 熊本市

4. 受賞

2016

  1. 吉本尚子:平成28年度日本生薬学会学術奨励賞.平成28年9月24日

2015

  1. 森直子,吉本尚子,小沼美紗都,鈴木秀幸,小寺幸広,恒吉唯充,斉藤和季:第33回日本植物細胞分子生物学会(東京)大会・シンポジウム 学生優秀発表賞.平成27年8月10日
  2. 斉藤和季:米国植物生理学会ASPB TOP AUTHERSに選出.平成27年8月20日
  3. 吉本尚子:平成27年度日本薬学会生薬天然物部会奨励研究賞.平成27年10月30日
  4. 斉藤和季:トムソン・ロイター社Highly Cited Researchers2015に選出.平成28年1月20日
  5. 斉藤和季:2016年度日本植物生理学会・学会賞.平成28年3月18日
  6. 高山廣光:平成27年度日本生薬学会生薬学会賞「生物活性アルカロイドの探索・合成・創薬化学研究」(2015)
  7. 金田結:第6回食品薬学シンポジウム優秀発表賞,ヒストン修飾に関わるポリコーム構成分子BMI1を標的とした天然物の探索.(2015)
  8. 米山達朗:日本生薬学会小城海外派遣助成受賞,The 2015 International Chemical Congress of Pacific Basin Societies(米国・ハワイ).(2015)
  9. 高梨憲幸:日本薬学会第136年会(横浜)学生優秀発表賞, Akuammiline型インドールアルカロイドの全合成研究 (2016)
  10. 平間拓:日本薬学会第136年会(横浜)学生優秀発表賞,ミソハギ科植物含有ビフェニルキノリジジンアルカロイド類の不斉全合成研究. (2016)
  11. 田中光葉:日本薬学会第136年会(横浜)学生優秀発表賞, 放線菌からのHes1ビーズを用いた神経幹細胞分化を促進する天然物の探索 (2016)
  12. 金田結:日本薬学会第136年会(横浜)学生優秀発表賞, ヒストン修飾に関わるポリコーム構成分子BMI1を標的とした天然物の探索 (2016)
  13. 平成27年度 日本植物形態学会 「平瀬賞」Daisuke Maruyama, Ronny Vo¨ lz Hidenori Takeuchi, Toshiyuki Mori, Tomoko Igawa, Daisuke Kurihara, Tomokazu Kawashima, Minako Ueda, Masaki Ito, Masaaki Umeda, Shuh-ichi Nishikawa, Rita Groß-Hardt, and Tetsuya HigashiyamaRapid elimination of the persistent synergid through a cell fusion mechanism Cell 161(4):907-18(015)
  14. 平成27年度 第128回講演会 日本育種学会優秀発表賞 講演番号P048 「催涙成分合成酵素遺伝子を標的としたタマネギのゲノム編集」真壁壮、井川智子、今井真介、鴨井享宏、中村郁郎

5. 報道発表

2016

  1. 「〜薬用植物の進化の謎をひもとく〜 植物アルカロイドの生産性はアミノ酸代謝酵素の収斂分子進化に起因することを明らかに」千葉大学、九州工業大学、理化学研究所から共同プレスリリース(平成28年6月24日)
  2. 「アルカロイドで新知見、アミノ酸代謝酵素 分子進化に生成起因」化学工業日報(平成28年7月7日)
  3. 「植物のアルカロイドの生産性」科学新聞(平成28年7月8日)
  4. 「原始紅藻がストレス応答 植物ホルモン合成 東工大など発見」日刊工業新聞(2016年4月8日)

2015

  1. 「ニンニクの薬用成分を作る鍵となる遺伝子を発見 〜薬用・健康機能成分の効率的生産や創薬、育種に期待〜」千葉大学、理化学研究所、ハウス食品グループ本社、湧永製薬株式会社から共同プレスリリース(平成27年8月3日)
  2. 「千葉大と理研など、ニンニクの薬用成分を作る鍵となる遺伝子を発見」日経電子版(平成27年8月5日)
  3. 「ニンニク薬用成分生合成遺伝子を発見」化学工業日報(平成27年8月6日)
  4. 「国立研究開発法人理化学研究所、ニンニクの薬用成分を作る鍵となる遺伝子を発見」日経バイオテクONLINE(平成27年8月6日)
  5. 「千葉大、ニンニクの薬用効果の基となっている酵素遺伝子を発見」財経新聞(平成27年8月11日)
  6. 「千葉大グループ、ニンニク薬用成分鍵となる遺伝子発見」薬事日報(平成27年8月17日)
  7. 「ニンニクの薬用成分生産の鍵を握る遺伝子」科学新聞,(平成27年8月28日)
  8. 「植物が薬理作用をもつ天然物を合成する過程を解明」神戸大学、千葉大学から共同プレスリリース(平成28年3月18日)

6. 特許

2016

  1. 高山廣光: オピオイド鎮痛剤 (Opioid Analgesic). 米国出願 15/032,070 (2016)米国出願
  2. 高山廣光: オピオイド鎮痛剤 (Opioid Analgesic). 特願2015-545005 (2016)
  3. 石橋正己,原昇子,原康雅,石川直樹,酒井香奈江,五ノ井透:ナブセシンA、ナブセシンB、及びその製造方法.特願2016-120162 (2016)

2015

  1. Takayama, H.: Opioid analgesic with high metabolic stability, pharmaceutical composition containing it, and method for inducing analgesic effect. PCT Int. Appl., WO 2015064573 A1, 20150507 (2015)
  2. 2015.4.20 特願2015-086193「光源ユニット、栽培モジュール及び栽培方法」
  3. 2015.9.15 特願2015-181520「ネット状資材」