Publications (2010, 2011)

[Research Papers] [Presentations in Academic Meetings]

Research Papers

  1. Matsuyama, S., Aydan, A., Ode, H., Hata, M., Sugiura, W., Hoshino, T. : Structural and Energetic Analysis on the Complexes of Clinically-isolated Subtype C HIV-1 Proteases and Approved Inhibitors by Molecular Dynamics Simulation. J. Phys. Chem. B 114, 521-530 (2010)
  2. Mao, Y., Shang, Z., Imai, Y., Hoshino, T., Tero, R., Tanaka, M., Yamamoto, N., Yanagisawa, K., Urisu, T. : Surface-induced phase separation of a sphingomyelin/cholesterol/ganglioside GM1-planar bilayer on mica surfaces and microdomain molecular conformation that accelerates Abeta oligomerization. Biochimica et Biophysica Acta 1798, 1090-1099 (2010)
  3. Sano, E., Li, W., Yuki, H., Liu, X., Furihata, T., Kobayashi, K, Chiba, K., Neya, S., Hoshino, T. : Mechanism of the decrease in catalytic activity of human cytochrome P450 2C9 polymorphic variants, investigated by computational analysis. J. Computat. Chem. 31, 2746-2758 (2010)
  4. Neya, S., Suzuki, M., Hoshino, T., Ode, H., Imai, K., Komatsu, T., Ikezaki, A., Nakamura, M., Furutani, Y., Kandori, H. : Molecular Insight of Intrinsic Heme Distortion to the Ligand Binding in Hemoprotein. Biochemistry 49, 5642-5650 (2010)
  5. Suzuki, S., Urano, E., Hashimoto, C., Tsutsumi, H., Nakahara, T., Tanaka, T., Nakanishi, Y., Maddali, K., Han, Y., Hamatake, M., Miyauchi, K., Pommier, Y., Beutler, J. A., Sugiura, W., Fuji, H., Hoshino, T., Itotani, K., Nomura, W., Narumi, T., Yamamoto, N., Komano, J. A., Tamamura, H. : Peptide HIV-1 Integrase Inhibitors from HIV-1 Gene Products. J. Med. Chem. 53, 5356-5360 (2010)
  6. Shang, Z., Mao, Y., Tero, R., Liu, X., Hoshino, T., Tanaka, M., Urisu, T. : Clustering effects of GM1 and formation mechanisms of interdigitated liquid disordered domains in GM1/SM/CHOL-supported planar bilayers on mica surfaces. Chem. Phys. Lett. 497, 108-114 (2010)
  7. Imai, Y., Liu, X., Yamagishi, J., Mori, K. Neya, S. Hoshino, T. : Computational Analysis of Water Residence on Ceramide and Sphingomyelin Bilayer Membranes. J. Mol. Graphics Model. 29, 461-469 (2010)
  8. Li, W., Shen, J., Tang, Y., Hoshino, T. : Exploring coumarin egress channels in human cytochrome P450 2A6 by random acceleration and steered molecular dynamics simulations. Proteins 79, 271-281 (2011)
  9. Yanagita H., Urano E., Matsumoto K., Ichikawa R., Takaesu Y., Ogata M., Murakami T., Wu H., Chiba J., Komano J., Hoshino T. : Structural and Biochemical Study on the Inhibitory Activity of Derivatives of 5-nitro-furan-2-carboxylic acid for RNase H Function of HIV-1 Reverse Transcriptase. Bioorg. Med. Chem. , 816-825 (2011)
  10. Neya, S., Kawaguchi, A. T. : Inherently distorted heme as a novel tool for myoglobin-based oxygen carrier. Artificial Organs , in press (2011)
  11. Mahmood M.I., Matsuo Y., Neya, S., Hoshino T. : Computational analysis on the binding of epitope peptide to human leukocyte antigen class I molecule A*2402 subtype. Chem. Pharm. Bull. (2011) in press

Reviews

Presentations in Academic Meetings

  1. Suzuki, M., Hoshino, T., Neya, S. : Synthesis and Characterization of β-Alkyl Substituted Hexaphyrin(1.1.1.1.1.1).5th International Symposium on Macrocyclic and Supramolecular Chemistry, P111（Poster）, Nara (2010.6.7)
  2. Neya, S. : Molecular Insight of Heme Deformation to the Ligand Binding to Hemoproteins. Sixth International Conference on Porphyrins and Phthalocyanines. S34-7 (Oral). New Mexico, USA. (2010.7.4-9)
  3. Ohgo, Y., Hashizume, D., Hayami, S., Mori, M., Nakamura, M., Neya, S., Takahashi, K. : Response of the dpi-ppi Interaction to the Environmental Stimuli in Iron(III) Heme. Sixth International Conference on Porphyrins and Phthalocyanines. S34-8 (Oral). New Mexico, USA. (2010.7.4-9)
  4. Liu X., Neya S., Hoshino T. :Dynamics motions of G-Protein-Coupled receptors embedded in lipid bilayer membranes with different kinds of molecular components. CBI 2010 annual meeting, Proceedings of CBI 2010, P1-04,CBI 2010 annual meeting, Tokyo(2010.9.15)
  5. Neya, S., Suzuki, M., Hoshino, T. : Functional Ａnomaly of Hemoprotein Induced by Nonplanar Deformation of Heme. 60th Anniversary Conference in Japanese Coordination Chemistry. 2IB-18 (Invited Oral). Osaka. (2010.9.27-30)
  6. Ohgo,Y., Hashizume, D., Akahashi, K., Moris, H., Hayami, S., Neya, S., Nakamura, M. : Exploration and utilization of heme electronic structure. 60th Anniversary Conference in Japanese Coordination Chemistry. 2IB-19 Osaka. （2010.9.27-30)
  7. Hoshino T., Yanagita H., Komano J. (Invited) : Development of the inhibitory compounds for RNase H enzymatic activity of HIV-1 reverse transcriptase.4th International Symposium on Nanomedicine (ISNM2010), O-29-05 Okazaki (2010.11.29)

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