Publication / 発表論文

125.

Regio-divergent Nickel Catalysis: Intramolecular [4+2] and [2+2] Cycloaddition Reactions Between Vinylallenes and Alkynes

Arai, S.; Inagaki, S.; Nakajima, M.; Nishida, A.

Chem. Commun. 2021, 57, 11268-11271.


124.

Regio- and stereoselective synthesis of cyclobutanes by nickel-catalyzed homodimerizative [2 + 2] cycloaddition using allenamides.

Kawata, Y.; Arai, S.; Nakajima, M.; Nishida, A.

Tetrahedron Lett. 2021, 69, 152974.


123.

Trichloromethylative Olefin Cycloamination by Photoredox Catalysis
Shinji Harada, Ryuya Masuda, Takahiro Morikawa, and Atsushi Nishida

Eur. J. Org. Chem. 2021, 4531-4535.


122.

Acacienone, a terpenoid-like natural product having an unprecedented C20 framework isolated fromAcacia mangiumleaves

Yasumasa Hara, Yuichi, Totsugi, Hiroshi Ichikawa, Shinji Harada, Kazuki Fujii, Firoj Ahmed, Samir K. Sadhu, Midori A. Arai, Masami Ishibashi

J. Nat. Med. 2021, 75, 99-104.


121.

CCL113, a novel sulfonamide, induces selective mitotic arrest and apoptosis in HeLa and HepG2 cells

Ruirong Yi, Yoshifumi Ohno, Zheng Tian, Shuhan Guo, Weiwei Chen, Xue Ma, Nan Nwe Win, Qisen Li, Majid Vahed, Kengo Saito, Shingo Nakamoto, Akiko Suganami, Naohisa Isegawa, Keisuke Yoshida, Shinji Harada, Yutaka Tamura, Atsushi Nishida, Hiroshi Shirasawa

Oncology Reports 2020, 44, 2770-2782.


120.

Catalytic Synthesis of Optically Active Polycyclic Heterocyclic Compounds

Shinji Harada

Yakugaku Zasshi 2020, 140, 1213-1224.


119.

Direct Synthesis of Enones by Visible-Light-Promoted Oxygenation of Trisubstituted Olefins Using Molecular Oxygen

Shinji Harada, Daiki Matsuda, Takahiro Morikawa, Atsushi Nishida

Synlett 2020, 31, 1372-1377.

(Featured in Org. Chem. Highlights 2021, Sep.13, Oxidation)


118.

Synthesis of Nitrogen Heterocycles through Cyanative Cyclization and Cycloaddition Reactions under Transition Metal Catalysis
Shigeru Arai, Atsushi Nishida
Heterocycles 2020, 100, 1949-1978.


117.

Optically Active Helical Lanthanide Complexes: Storable Chiral Lewis Acidic Catalysts for Enantioselective Diels-Alder Reaction of Siloxydienes

Shinji Harada, Saki Nakashima, Shihori Sekino, Wakana Oishi, and Atsushi Nishida

Chem. Asian J. 2020, 15, 483-486.


116.

Cobalt-catalyzed hydrocyanation and hydroarylation of enamines.

Arai, S.; Sato, Y.; Ito, N.; Nishida, A.

Tetrahedron Lett. 2019, 60, 151314-151317.


115.

Nickel-catalyzed [2+2] cycloaddition reaction using bisallenes.

Arai, S.; Kawata, Y.; Amako, Y.; Nishida, A.

Tetrahedron Lett. 2019, 60, 151168-151171.


114.

Regioselective [2+2+2] cycloaddition reaction using allene-ynes with simple allenes under nickel catalysis.

Arai, S.; Izaki, A.; Amako, Y.; Nakajima, M.; Uchiyama, M.; Nishida, A.

Adv. Syn. Catal. 2019, 361, 4882-4887.

Selected as Very Important Publication (VIP) and front cover picture.


113.

Cobalt-catalyzed cyclization with the introduction of cyano, acyl and aminoalkyl groups.

Hori, H.; Arai, S.; Nishida, A.

Org. Biomol. Chem. 2019, 17, 4783-4788.


112.

Fungal natural alkaloid schizocommunin activates the aryl hydrocarbon receptor pathway

Roxana Filip, Tyler A. Shaw, Atsushi Nishida, and John Paul Pezacki

Med. Chem. Commun. 2019, 10, 985-990.


111.

One-Pot Synthesis of Cycloocta[b]indole through Formal [5+3] Cycloaddition Using Donor-Acceptor Cyclopropanes

Akito Okabe, Shinji Harada, Takuya Takeda, and Atsushi Nishida

Eur. J. Org. Chem. 2019, 3916-3920.


110.

Catalytic and Enantioselective Diels-Alder Reaction of Siloxydienes

Shinji Harada, and Atsushi Nishida

Asian J. Org. Chem. 2019, 8, 732-745.


109.

ニッケル触媒を用いる炭素炭素多重結合へのヒドロシアノ化反応とその応用

荒井秀、天児由佳、堀弘人、西田篤司

有機合成化学協会誌、2019, 77, 341-349.


108.

Nickel-catalyzed Hydrocyanation of Allenes and Its Application

Arai, S.

Chem. Pharm. Bull. 2019, 67, 397-403.


107.

Nickel-catalyzed regioselective hydrocyanation of terminal alkynes by assistance of a tosyl group.

Arai, S.; Nakazawa, K.; Yang, X.-F.; Nishida, A.

Tetrahedron 2019, 75, 2482-2485.


106.

Cu-catalyzed regio- and stereoselective sulfonylation of multi-substituted allenes.

Shigeru Arai, Koki Matsumoto, Atsushi Nishida.

Tetrahedron 2019, 75, 1145-1148.


105.

Total Synthesis of Lundrines and Related Alkaloids

Shigeru Arai, Masaya Nakajima,AtsushiNishida.

J. Synth. Org. Chem., Jpn. 2018, 76, 668-677.


104.

Development of a new doubly-labeled fluorescent ceramide probe for monitoring the metabolism of sphingolipids in living cells

YabinWang,JunyaKasahara,KazuyukiYamagata,HiroyukiNakamura,ToshihikoMurayama,NoriyukiSuzuki,AtsushiNishida.

Bioorg. Med. Chem. Lett. 2018, 28, 3222-3226.


103.

Cyclohepta[b]indole Synthesis through [5+2] Cycloaddition: Bifunctional Indium(III)-Catalyzed Stereoselective Construction of 7-Membered Ring Fused Indoles

Takuya Takeda, Shinji Harada, Akito Okabe, Atsushi Nishida

J. Org. Chem. 2018, 83, 11541-11551.


102.

Enantioselective carbonyl-ene-type cyclization of α-ketoester and 2-substituted vinylsilane catalyzed by a chiral Cu-BOX complex

HarukaHomma,ShinjiHarada,AtsushiNishida

Tetrahedron Lett. 2018, 59, 2755-2758.


101.

 Formal Synthesis of (±)-Quebrachamine through regio- and stereoselective hydrocyanation of arylallene

Kouki Matsumoto, Shigeru Arai, Atsushi Nishida

Tetrahedron 2018, 74, 2865-2870.

100.

 Total Synthesis of Carbazomycins A and B

 Siyuan Wu, Shinji Harada, Takahiro Morikawa, and Atsushi Nishida

 Chem. Pharm. Bull. 2018, 66, 178-183.


99.

Enantioselective total synthesis of a natural hydrocarbazolone alkaloid, identification of its stereochemistry, and revision of its spectroscopic data

Siyuan Wu, Shinji Harada, Takahiro Morikawa, and Atsushi Nishida

Tetrahedron: Asymmetry 2017, 28, 1083-1088.


98.

Olefin-migrative Cleavage of Cyclopropane Rings through the Nickel-catalyzed Hydrocyanationof Allenes and Alkenes.

Hori, H. Arai, S., Nishida A.

Adv. Syn. Catal. 2017, 359, 1170.


97.

Transfer of Axial Chirality Through the Nickel-catalyzed Hydrocyanation of Chiral Allenes.

Amako Y. Arai, S., Nishida A.

Org. Biomol. Chem. 2017, 15, 1612-1617.


96.

Catalytic and Enantioselective Diels-Alder Reaction of Silyloxydiene That Incorporates a Pyrrolidine Ring, and Its Application to the Construction of Chiral Tri- and Tetracyclic Skeletons

Shinji Harada, Saki Nakashima, Wataru Yamada, Takahiro Morikawa, and Atsushi Nishida
Heterocycles2017, 95, 872-893.


95.

Construction of Optically Active Isotwistanes and Aminocyclitols Using Chiral Cyclohexadiene as a Common Intermediate

Shinji Harada, Kexin Li, Ryuto Kino, Takuya Takeda, Chia-Hsien Wu, Shiharu Hiraoka, and Atsushi Nishida

Chem. Pharm. Bull. 2016, 64(10), 1474-1483.


94

Furan-Iminium Cation Cyclization (FIC) in A Total Synthesisof Manzamine Alkaloids

Tokumaru,K.; Ohfusa,T.; Arai,S.; Nishida, A.

J. Antibiotics2016, 69, 340-343.


93

Total Syntheses of (+)-Grandilodine C and (+)-Lapidilectine B and Determination of their Absolute Stereochemistry

Masaya Nakajima, Shigeru Arai and Atsushi Nishida

Angew. Chem. Int. Ed. 2016, 55, 3473-3476.

<highlighted by SYNFACTS 2016, 12, 437.>


92

Catalytic Asymmetric Nazarov Cyclization of Heteroaryl Vinyl Ketones through a Crystallographically Defined Chiral Dinuclear Nickel Complex

Takuya Takeda, Shinji Harada, and Atsushi Nishida

Org. Lett. 2015,17 (21), 5184–5187.


91

Chiral Holmium Complex-Catalyzed Synthesis of Hydrocarbazole from Siloxyvinylindole and Its Application to the Enantioselective Total Synthesis of (–)-Minovincine

Takahiro Morikawa, Shinji Harada, and Atsushi Nishida

J. Org. Chem. 2015, 80, 8859-8867.


90

A New Protocol for Nickel-catalysed Regio- and Stereoselective Hydrocyanation of Allenes.

Shigeru Arai, Hiroto Hori, Yuka Amako, and Atsushi Nishida.

Chem. Commun. 2015, 51, 7493-7496.


89

Asymmetric Total Synthesis of (-)-Lundurine B and Determination of Its Absolute Stereochemistry.

Masaya Nakajima, Shigeru Arai, and Atsushi Nishida.

Chem. Asian J. 2015, 10, 1065-1070.


88

Catalytic and Enantioselective Synthesis of a Key Intermediate of the MCHr1 Antagonist AMG 076.

Shinji Harada, Haruka Ishii, Daisuke Shirasaki, and Atsushi Nishida.

HeteroCycles 2015, 90, 967-977.


87

Trafficking of Acetyl-C16-Ceramide-NBD with Long-Term Stability and No Cytotoxicity into the Golgi Complex

T. Makiyama, H. Nakamura, N. Nagasaka, H. Yamashita, T. Honda, N. Yamaguchi, A. Nishida and T. Murayama

Traffic 2015, 16, 476-492.


86

Stereoselective synthesis of chiral hydrocarbazoles via the catalytic Diels-Alder reaction of siloxyvinylindole and cyclic Z-olefin.

Keisuke Yoshida, Takahiro Morikawa, Naoto Yokozuka, Shinji Harada, and Atsushi Nishida.

Tetrahedron Lett. 2014, 55, 6907-6910.


85

A Concise and Versatile Synthesis of Alkaloids from Kopsia tenuis: Total Synthesis of (±)-Lundurine A and B.

Shigeru Arai, Masaya Nakajima, and Atsushi Nishida.

Angew. Chem. Int. Ed. 2014, 53, 5569-5571.

<highlighted by SYNFACTS 2014, 10, 789.>


84

Total Synthesis of (±)-Lundurine B.

Masaki Hoshi, Osamu Kaneko, Masaya Nakajima, Shigeru Arai, and Atsushi Nishida.

Org. Lett. 2014, 16, 768-771.

<highlighted by SYNFACTS 2014, 10, 338.>


83

A 2-Benzothiazolylphenyl Group Accelerates the Intramolecular [2+2] Cycloaddition of Allene-Ynes.

Hiroto Hori, Shigeru Arai and Atsushi Nishida.

Asian J. Org. Chem. 2014, 3, 41-43.


82

Total Synthesis of Schizocommunin and Revision of Its Structure.

Uehata, Koji; Kimura, Naoki; Hasegawa, Kazuya; Arai, Shigeru; Nishida, Mayumi; Hosoe, Tomoo; Kawai, Ken-ichi; Nishida, Atsushi.

Journal of Natural Products 2013, 76(11), 2034-2039.


81

Catalytic Cyanation of Carbon-Carbon Triple Bonds Through a Three-Component Cross-Coupling Reaction under Nickel Catalysis.

Yang, Xiaofei; Arai, Shigeru; Nishida, Atsushi.

Advanced Synthesis & Catalysis 2013, 355(14-15), 2974-2981.


80

Chiral Holmium Complex-Catalyzed Diels-Alder Reaction of Silyloxyvinylindoles: Stereoselective Synthesis of Hydrocarbazoles.

Shinji Harada, Takahiro Morikawa, and Atsushi Nishida.

Organic Letters 2013, 15(20), 5314-5317.


79

Regioselective Hydronickelation of Allenes and Its Application to the Hydrocyanative Carbocyclization Reaction of Allene-Ynes and Bis-Allenes.

Amako, Yuka; Hori, Hiroto; Arai, Shigeru; Nishida, Atsushi.

Journal of Organic Chemistry 2013, 78(21), 10763-10775


78

Development of catalytic and enantioselective Diels-Alder reaction of electron-rich dienes using chiral rare-earth metal complex.

Shinji Harada, Takahiro Morikawa, Shiharu Hiraoka, and Atsushi Nishida.

J. Synth. Org. Chem., Jpn2013, 71(8),818-829.


77

Hydrocyanative Cyclization and Three-Component Cross-Coupling Reaction between Allenes and Alkynes under Nickel Catalysis.

Shigeru Arai, Yuka Amako, Xiaofei Yang and Atsushi Nishida.

Angew. Chem. Int. Ed. 2013, 52(31), 8147-8150.


76

AntiCarbocyanative Cyclization of Enynes under Nickel Catalysis.

Tomohiro Igarashi, Shigeru Arai, and Atsushi Nishida.

J. Org. Chem.2013, 78(9), 4366-4372.


75

Palladium-Catalyzed Cyanation of Non-Activated Alkynes; Development of Cyanopalladationand Its Application to Cyclization and Cycloaddition Reactions.

Arai, S.; Nishida, A.

Synlett 2012, 23, 2880-2893. (invited accounts).


74

Abnormal Ito-Saegusa oxidation of TIPS enol ether assisted by a hydroxy group on a side chain.

Shiharu Hiraoka, Shinji Harada, and Atsushi Nishida.

Tetrahedron Lett. 2011, 52(24), 3079-3082.


73

Reactivity and stereoselectivity of the Diels-Alder reaction using cyclic dienophiles and siloxyaminobutadienes.

Toshiyuki Ohfusa, and Atsushi Nishida.

Tetrahedron 2011, 67(10), 1893-1906.


72

Catalytic dicyanative 5-exo- and 6-endo-cyclization triggered by cyanopalladation of alkynes.

Shigeru Arai, Yuka Koike, and Atsushi Nishida.

Adv. Synth. Catal. 2010, 352, 893-900.


71

Catalytic Dicyanative [4 + 2] Cycloaddition Triggered by Cyanopalladation Using Ene-Enynes and Cyclic Enynes with Methyl Acrylate.

Shigeru Arai, Yuka Koike, Hirohiko Hada, and Atsushi Nishida.

J. Org. Chem. 2010, 75, 7573-7579.


70

Catalytic Dicyanative [4+2] Cycloaddition Triggered by Cyanopalladation of Conjugated Enynes under Aerobic Conditions.

Shigeru Arai, Yuka Koike, Hirohiko Hada, and Atsushi Nishida.

J. Am. Chem. Soc. 2010, 132, 4522-4523.


69

Catalytic Enantioselective Total Synthesis of (–)-Platyphyllide and Its Structural Revision.

Shiharu Hiraoka, Shinji Harada, and Atsushi Nishida.

J. Org. Chem. 2010, 75 (11), 3871-3874.


68

Continuous-Flow C-H Borylation of Arene Derivatives.

Tsuyoshi Tagata, Mayumi Nishida, and Atsushi Nishida.

Adv. Synth. Catal. 2010, 352, 1662-1666.


67

Newly synthetic ceramide-1-phosphate analogs; their uptake, intracellular localization, and roles as an inhibitor of cytosolic phospholipase A(2)α and inducer of cell toxicity.

Makiyama Tomohiko; Nagasaka Nobuo; Houjyo Yuuya; Yamaura Erika; Nakamura Hiroyuki; Koide Yuuki; Nishida Atsushi; Murayama Toshihiko.

Biochemical pharmacology 2010, 80(9), 1396-406.


66

Palladium-Catalyzed Cyanation of Carbon-Carbon Triple Bonds under Aerobic Conditions.

Arai, S.; Sato, T.; Koike, Y.; Hayashi, M.; Nishida, A.

Angew. Chem. Int. Ed. 2009, 48, 4528-4531.

Highlighted in Synth. Org. Chem. Jpn. 2010, 68, 567.


65

Alantrypinone and its derivatives and Synthesis and antagonist activity toward insect GABA receptors.

Watanabe, Takayuki; Arisawa, Mitsuhiro; Narusuye, Kenji; Alam, Mohommad Sayed; Yamamoto, Kazumi; Mitomi, Masaaki; Ozoe, Yoshihisa; Nishida, Atsushi.

Bioorganic & Medicinal Chemistry 2009, 17(1), 94-110.


64

Asymmetric synthesis of hydroisoquinoline derivatives, a key intermediate for manzamine synthesis, by Diels-Alder reaction using 4-amino-2-siloxybutadiene.

Mihara, Yasuhiro; Matsumura, Tomoaki; Terauchi, Yuki; Akiba, Masakatsu; Arai, Shigeru; Nishida, Atsushi.

Bulletin of the Chemical Society of Japan 2009, 82(12), 1520-1527.


63

Catalytic 1,2-Dicyanation of Alkynes by Palladium(II) under Aerobic Conditions.

Arai, Shigeru; Sato, Takashi; Nishida, Atsushi.

Advanced Synthesis & Catalysis 2009, 351(11+12), 1897-1904.


62

Development of recyclable iridium catalyst for C-H borylation.

Tagata, Tsuyoshi; Nishida, Mayumi; Nishida, Atsushi.

Tetrahedron Letters 2009, 50(45), 6176-6179.


61

Effects of synthetic sphingosine-1-phosphate analogs on cytosolic phospholipase A2α-independent release of arachidonic acid and cell toxicity in L929 fibrosarcoma cells: the structure-activity relationship.

Shimizu, Masaya; Muramatsu, Yuki; Tada, Eiko; Kurosawa, Takeshi; Yamaura, Erika; Nakamura, Hiroyuki; Fujino, Hiromichi; Houjyo, Yuuya; Miyasaka, Yuri; Koide, Yuuki; Nishida, Atsushi; Murayama, Toshihiko.

Journal of Pharmacological Sciences (Tokyo, Japan) 2009, 109, 431-443.


60

Highly Enantioselective Diels-Alder Reaction of Danishefsky-Type Diene and Electron Deficient Olefins Catalyzed by an Yb(III)/Chiral Bis-urea Complex.

Shinji Harada, Nozomi Toudou, Shiharu Hiraoka, and Atsushi Nishida.

Tetrahedron Lett. 2009, 50, 5652-5655.


59

Highly Enantioselective Diels-Alder Reactions of Danishefsky Type Dienes with Electron-Deficient Alkenes Catalyzed by Yb(III)-BINAMIDE Complexes.

Yukinori Sudo, Daisuke Shirasaki, Shinji Harada and Atsushi Nishida.

J. Am. Chem. Soc. 2008, 130(38), 12588-12589.

<Highlighted by SYNFACTS 2008, 12, 1298.>


58

Preparation of Tethered Palladium Catalysis Supported on Gold(III) and Its Surface Characterization by X-ray Photoelectron Spectroscopy (XPS),

Rabbani M. Gulam,Masahiro Hamada, Ikuko Takamiya, Masahiko Shimoda, Satoshi Shuto, Atsushi Nishida, Shiro Tsukamoto, and Mitsuhiro Arisawa,

Bull. Chem. Soc. Jpn. 2008, 81(8), 1012–1018.


57

Novel Synthesis of Cinnolines and 1-Aminoindolines via Cu-Catalyzed Intramolecular N-Arylation of Hydrazines and Hydrazones Prepared from 3-Haloaryl-3-hydroxy-2-diazopropanoates,

Kazuya Hasegawa, Naoki Kimura, Shigeru Arai, and Atsushi Nishida,

J. Org. Chem., 2008, 73(16), 6363-6368.


56

Pharmacophore-Based Design of Sphingosine 1-phosphate-3 Receptor Antagonists That Include a 3,4-Dialkoxybenzophenone Scaffold,

Yuuki Koide, Kazuhiro Uemoto, Takeshi Hasegawa, Tomoyuki Sada, Akira Murakami, Hiroshi Takasugi, Atsuko Sakurai, Naoki Mochizuki, Atsuo Takahashi, and Atsushi Nishida,

J. Med. Chem. 2007, 50, 442-454.


55

Synthetic Study of Manzamine B; Synthesis of the Tricyclic Central Core by an Asymmetric Diels-Alder and RCM Strategy,

Tomoaki Matsumura, Masakatsu Akiba, Shigeru Arai, Masako Nakagawa and Atsushi Nishida,

Tetrahedron Letters. 2007, 48, 1265-1268


54

Catalytic Asymmetric Michael Reaction under Phase-Transfer Catalysis; Construction of Chiral Tetrasubstituted Carbon and its Application to the Synthesis of a Chiral Pyrrolidone,

Shigeru Arai, Fumie Takahashi, Riichiro Tsuji, and Atsushi Nishida, 

Heterocycles, 2006, 67, 495-501.


53

Synthesis of alpha-Diazo-beta-hydroxyesters through a One-Pot Protocol by Phase-Transfer Catalysis: Application to Enantioselective Aldol-Type Reaction and Deastereoselective Synthesis of alpha-Amino-beta-hydroxyester Derivatives, Kazuya Hasegawa, Shigeru Arai, and Atsushi Nishida, Tetrahedron, 2006, 62, 1390-1401.


52

Development of a Method for Preparing a Highly Reactive Stable and Recyclable Palladium Catalyst Supported on GaAs(001): A Three-component Catalyst, {Pd}-S-GaAs(001), and Its Properties, Mitsuhiro Arisawa, Ikuko Takamiya, Masahiko Shimoda, Shiro Tsukamoto, Yasuhiko Arakawa and Atsushi Nishida, Advanced Synthesis & Catalysis, 2006, 348, 1063-1070.


51

Highly Reactive Organopalladium Catalyst Formed on Sulfur-terminated GaAs(001)-(2x6) Surface, Ikuko Takamiya, Shiro Tsukamoto, Masahiko Shimoda, Mitsuhiro Arisawa, Atsushi Nishida, and Yasuhiko Arakawa, Japanese Journal of Applied Physics, 2006, 45(18), L475-L477.


50

Development of Novel Isomerization and Cycloisomerization using a Ruthenium Hydride with N-heterocyclic Carbene and Its Application to the Synthesis of Heterocycles, Mitsuhiro Arisawa, Yukiyoshi Terada, Kazuyuki Takahashi, and Atsushi Nishida, J. Org. Chem. 2006, 71, 4255-4261. #18th, a Most-Cited Articles in J. Org. Chem. (2006).


49

Stereoselective Furan-Iminium Cation Cyclization in the Construction of the Core Structure of Manzamine A, Kazuyuki Tokumaru, Shigeru Arai and Atsushi Nishida, Organic Letters, 2006, 8, 27-30.


48

Synthesis of a-Diazo-b-hydroxyesters through a One-Pot Protocol by Phase-Transfer Catalysis: Application to Enantioselective Aldol-Type Reaction and Deastereoselective Synthesis of a-Amino-b-hydroxyester Derivatives, Kazuya Hasegawa, Shigeru Arai, and Atsushi Nishida, Tetrahedron, 2006, 62, 1390-1401.


47

Catalytic Asymmetric Michael Reaction under Phase-Transfer Catalysis; Construction of Chiral Tetrasubstituted Carbon and its Application to the Synthesis of a Chiral Pyrrolidone, Shigeru Arai, Fumie Takahashi, Riichiro Tsuji, and Atsushi Nishida, Heterocycles, 2006, 67, 495-501.


46

A Facile and Regioselective Dealkylation of Arylalkylethers Using Niobium(V) Pentachloride, Yukinori Sudo, Shigeru Arai, and Atsushi Nishida, Euro. J. Org. Chem. 2005, accepted.


45

Facile Synthesis of Vicinal Diamines Promoted by Low-valent Niobium: The Preparation of Chiral Octahydrobisisoquinolines and its Application to Catalytic Asymmetric Synthesis, Shigeru Arai, Satoshi Takita, and Atsushi Nishida, Euro. J. Org. Chem. 2005, 5262-5267.


44

Involvement of p38 MAP Kinase-Mediated Cytochrome C Release on Shingosine-1-phosphate (S1P)- and N-Monomethyl-S1P-induced Cell Death of PC12 Cells, Yuko Takashiro, Hiroyuki Nakamura, Yuuki Koide, Atsushi Nishida, Toshihiko Murayama, Biochemical Pharmacology, 2005, 70 (2), 258-265.


43

Synthesis of the Putative Structure of Fistulosin Using the Ruthenium-Catalyzed Cycloisomerization of Diene, Yukiyoshi Terada, Mitsuhiro Arisawa, and Atsushi Nishida, J. Org. Chem., 2005, 71(3), 1269-1272.


42

Diastereoselective Fischer-Type Pyrroloindole Synthesis and Its Application to the Synthesis of Chiral Pyrroloindole Alkaloids, Atsushi Nishida, Satoru Ushigome, Ayako Sugimoto, and Shigeru Arai, Heterocycles, 2005, 66, 181-185.


41

Preparation of N-Sulfonyl-2-quinolinone using Ring-Closing Metathesis (RCM), Mitsuhiro Arisawa, Chumpol Theeraladanon and Atsushi Nishida, Heterocycles, 2005, 66, 683-668.


40

Total Synthesis of (+)-(S)-Angustureine and Determination of the Absolute configuration of the Natural Product Angustureine, Chumpol Theeraladanon, Mitsuhiro Arisawa, Masako Nakagawa, Atsushi Nishida, Tetrahedron Asymmetry, 2005, 16, 827-831.


39

Niobium Pentachloride-Silver Perchlorate as an Efficient Catalyst in the FriedelミCrafts Acylation and SakuraiミHosomi Reaction of Acetals, Shigeru Arai, Yukinori Sudo, and Atsushi Nishida, Tetrahedron, 2005, 61, 4639-4642.


38

One-pot Synthesis of a-Diazo-b-hydroxyesters under Phase-Transfer Catalysis and Application to the Catalytic Asymmetric Aldol Reaction, Shigeru Arai, Kazuya Hasegawa and Atsushi Nishida, Tetrahedron Letters, 2004, 45, 1023-1026.


37

A Novel Synthesis of Substituted Quinolines Using Ring-Closing Metathesis (RCM): Its Application to the Synthesis of Key Intermediates for Anti-malarial Agents, Chumpol Theeraladanon, Mitsuhiro Arisawa, Atsushi Nishida and Masako Nakagawa, Tetrahedron, 2004, 68, 3017-3035.


36

A Highly Diastereoselective Pinacol Coupling Reaction of Aldehydes and Ketones Using Low-valence Niobium Generated from Nb(V), Shigeru Arai, Yukinori Sudo and Atsushi Nishida, Chem. Pharm. Bull., 2004, 52 (2), 287-288.


35

Cycloisomerization Promoted by the Combination of a Ruthenium Carbene Catalyst and Vinyloxytrimethylsilane, and its Application to the Synthesis of Heterocyclic Compounds; 3-Methylene-2, 3-dihydroindoles and 3-Methylene-2,3-dihydrobenzofurans, Yukiyoshi Terada, Mitsuhiro Arisawa, and Atsushi Nishida, Angew. Chem. Int. Ed., 2004, 43 4063-4067.


34

Novel Synthesis of Fused Indoles by the Palladium-Catalyzed Cyclization of N-Cycloalkenyl-o-haloanilines, Takeshi Watanabe, Shigeru Arai, Atsushi Nishida, Synlett, 2004, 907-909.


33

A Simple and Regioselective Carbon-Oxygen Bond Cleavage Using Niobim(V), Shigeru Arai, Yukinori Sudo and Atsushi Nishida, Synlett, 2004, 1104-1106.


32

Novel Palladium Catalyst Supported on GaAs(001) Passivated by Ammonium Sulfide, Ikuko Takamiya, Shiro Tsukamoto, Masahiko Shimoda, Naoki Misyashita, Mitsuhiro Arisawa, Yasuhiko Arakawa and Atsushi Nishida, Chem. Lett. 2004, 33 (9), 1208-1209.


31

Effect of Synthetic Sphingosine-1-phoshate analogs on Arachidonic Acid Metabolism and Cell Death, Hiroyuki Nakamura, Yuko Takashiro, Tetsuya Hirabayashi, Syunji Horie, Yuuki Koide, Atsushi Nishida, Toshihiko Murayama, Biochemical Pharmacology, 2004, 68, 2187-2196.


30

General Method for the Synthesis of Chiral 2,3-Bisarylmethoxy-1,4-butanediols from (L)-(+)-Tartarate, Riichiro Tsuji, Shigeru Arai, Atsushi Nishida, Synthesis, 2004, 960-966 (Featured Article).


29

Asymmetric Total Synthesis of (-)-Nakadomarin A, Koji Ono, Masako Nakagawa, and Atsushi Nishida, Angew. Chem. Int. Ed., 2004, 43, 2020-2023.


28

Synthesis of (3-Indolyl)heteroaromatics by Suzuki-Miyaura Coupling and Their Inhibitory Activity in Lipid Peroxidation, Atsushi Nishida, Naoki Miyashita, Mihoko Fuwa, Masako Nakagawa, Heterocycles, 2003, 59, 473-476.


27

Practical Synthesis of a 3,4,4a,5,8,8a-Hexahydro-2H-isoquinolin-1,6-dione Ring Ssytem by the Diels-Alder Reaction of an Optically Active Dienophile, a 5,6-Dihydro-1H-pyridine-2-one Derivative, with Siloxydiene, Masako Nakagawa, Hideharu Uchida, Koji Ono, Yoshiyuki Kimura, Mariko Yamabe, Takeshi Watanabe, Riichiro Tsuji, Masakatsu Akiba, Yukiyoshi Terada, Dai Nagaki, Sachiko Ban, Naoki Miyashita, Takuya Kano, Chumpol Theeraladanon, Keisuke Hatakeyama, Mitsuhiro Arisawa and Atsushi Nishida, Heterocycles, 2003, 59, 721-733.


26

Efficient Synthetic Approach to Optically Active b-Carboline Derivatives via Pictet-Spengler Reaction Promoted by Trimethylchlorosilane, Riichiro Tsuji, Masako Nakagawa, Atsushi Nishida, Tetrahedron Asymmetry, 2003, 14, 177-180.


25

The First Total Synthesis of Nakadomarin A , Toshiaki Nagata, Masako Nakagawa, and Atsushi Nishida, J. Am. Chem. Soc., 2003, 125 (25), 7484-7485.


24

Diene RCM in the Presence of a Protected Alkyne, Koji Ono, Toshiaki Nagata and Atsushi Nishida, Synlett, 2003, 1207-1209.


23

Imino Ene Reaction Catalyzed by Ytterbium(III) Triflate and TMSCl or TMSOTf, Masamichi Yamanaka, Atsushi Nishida, Masako Nakagawa, J. Org. Chem., 2003, 68, 3112-3120.


22

Studies on the Asymmetric Diels-Alder Reaction of Dihydropyridine-2-one with Silyloxydiene, Masamichi Yamanaka, Toshiaki Nagata, Yoshino Nakajima, Atsushi Nishida, and Masako Nakagawa, Heterocycles, 2002, 56, 283-290.


21

Stereoselectivity in Ring-Closing Olefin Metathesis (RCM) of Tethered Di-hexenoyl Derivatives, Mitsuhiro Arisawa, Kaneko Hiroaki, Atsushi Nishida, Masako Nakagawa, J. Chem. Soc. Perkin Trans 1, 2002, 959-964.


20

Pictet-Spengler Reaction of Nitrones and Imines Catalyzed by Yb(OTf)3-TMSCl, Riichiro Tsuji, Masamichi Yamanaka, Atsushi Nishida, Masako Nakagawa, Chem. Lett. 2002, 428-429.


19

An Intriguing Effect of Yb(OTf)3-TMSCl in the Halogenation of 1,1-Disubstituted Alkenes by NXS: Selective Synthesis of Allyl Halides, Masamichi Yamanaka, Mitsuhiro Arisawa, Atsushi Nishida, Masako Nakagawa, Tetrahedron Lett., 2002, 43, 2403-2404.


18

Novel Skeletal Rearrangement of Hydroindan Derivatives into Hydroazulenones via an Alkoxy Radical, Mizuko Goto, Irei Miyoshi, Yusuke Ishii, Yukie Ogasawara, You-Ichirou Kakimoto, Shinji Nagumo, Atsushi Nishida, Norio Kawahara, Mayumi Nishida, Tetrahedron, 2002, 58, 2339-2350.


17

Development of Novel EDG3 Antagonists Using 3D-Database Search and Their Structure Activity Relationship, Yuuki Koide, Takeshi Hasegawa, Atsuo Takahashi, Akira Endo, Naoki Mochizuki, Masako Nakagawa, Atsushi Nishida, J. Med. Chem., 2002, 45, 4629-4638.


16

Simple Synthesis of Racemic Pyrrolo[2,3-b]indoles; Formal Total Synthesis of (+1)-Physostigmine, Riichiro Tsuji, Atsushi Nishida, Masako Nakagawa, Heterocycles, 2002, 58, 587-593.


15

Novel Synthetic Method for 2,3-Dihydro-3-halo-3-methylindole from N-Acetyl-2-isopropenylaniline by Intramolecular Haloamination, Mitsuhiro Arisawa, Yuko Ando, Masamichi Yamanaka, Masako Nakagawa, Atsushi Nishida, Synlett, 2002, (9), 1514-1516.


14

Novel Organopalladium Catalyst Material Formed on a Sulfur-Terminated GaAs(001) Surface, Mitsuhiro Arisawa, Shiro Tsukamoto, Masahiko Shimoda, Markus Pristovsek, Atsushi Nishida, Japanese Journal of Applied Physics, 2002, 41, L1197-L1199.


13

Selective Isomerization of Terminal Olefin Catalyzed by a Ruthenium Complex: A Novel Indole Synthesis via Ring-Closing Metathesis (RCM), Mitsuhiro Arisawa, Yukiyoshi Terada, Masako Nakagawa, Atsushi Nishida, Angew. Chem. Int. Ed., 2002, 41, 4732-4734.


12

Phase-Transfer-Catalyzed Asymmetric Michael Reaction using Newly-Prepared Chiral Quaternary Ammonium Salts Derived from L-Tartrate, Shigeru Arai, Riichiro Tsuji and Atsushi Nishida, Tetrahedron Lett., 2002, 43, 9535-9537.


11

Structural Requirements of Sphingosine Molecules for Inhibition of DNA Primase : Biochemical and Computational Analyses, Yasutomo Ito, Keiko Tamiya-Koizumi, Yuuki Koide, Masako Nakagawa, Tomohiko, Kawade, Atsushi Nishida, Takashi Murate, Masaharu Takemura, Motoshi Suzuki, Shonen Yoshida, Biochemistry, 2001, 40, 11571-11577.


10

Synthesis of Substituted 1,2-Dihydroquinolines and Quinolines Using Ene-ene Metathesis and Ene-enol Ether Metathesis, Mitsuhiro Arisawa, Chumpol Theeraladanon, Atsushi Nishida, and Masako Nakagawa, Tetrahedron Lett., 2001, 42, 8029-8033.


9

Synthetic Approach towards Nakadomarin A: Efficient Synthesis of the Central Tetracyclic Core, Toshiaki Nagata, Atsushi Nishida, and Masako Nakagawa, Tetrahedron Lett., 2001, 42, 8345-8349.


8

Ytterbium(III) Triflate/TMS-Cl; Efficient Catalyst for the Imino Ene Reaction, Masamichi Yamanaka, Atsushi Nishida, Masako Nakagawa, Organic Letters . 2000, 2 (2), 159-161.


7

An Efficient Synthesis of Optically Active Physostigmine from Tryptophan via Alkylative Cyclization, Michiaki Kawahara, Atsushi Nishida, Masako, Nakagawa, Organic Letters . 2000, 2 (5), 675-678.


6

Solid Phase Synthesis of 5-(3-Indollyl)oxazoles Having Inhibitory Activity of Lipid Peroxidation, Atsushi Nishida, Fuwa Mihoko, Shunji Naruto, Yuichi Sugano, Hironao Sito, and Masako Nakagawa, Tetrahedron Lett., 2000, 41 (24), 4791-4794.


5

Novel Axially Chiral Macrolactam by Grubbs Ring-Closing Methathesis (RCM), Mitsuhiro Arisawa, Hiroaki Kaneko, Atsushi Nishida, Kentaro Yamaguchi, Masako Nakagawa, Synlett 2000, (6), 841-843.


4

Concise Synthesis of Azacycloundecenes Using Ring-Closing Metathesis (RCM), Mitsuhiro Arisawa, Chiaki Kato, Hiroaki Kaneko, Atsushi, Nishida, Masako Nakagawa, J. Chem. Soc. Perkin Trans 1, 2000, 1873-1876.


3

Skeletal Rearrangement via Alkoxy Radical: Conversion of Epoxydecalin Thiocarbonyl-imidazolides to Bicyclo[6.3.0]undecanones and Bicyclo[5.3.1]undecanones. You-Ichirou Kakimoto, Yukie Ogasawara, Atsushi Nishida, Norio Kawahara, Mayumi Nishida, and Hiroaki Takayanagi, Tetrahedron , 2000, 56 (37), 7173-7185.


2

Construction of Chiral 1,2-Cycloalkanopyrrolidines from L-Proline Using Ring Closing Metathesis (RCM), Mitsuhiro Arisawa, Maki Takahashi, Emiko Takezawa, Takenobu Yamaguchi, Yasuhiro Torisawa, Atsushi Nishida, Masako Nakagawa, Chem. Pharm. Bull. Jpn. 2000, 48 (10) 1593-1596.


1

Application of New Chiral Auxiliaries, trans-2-(N-Arylsulfonyl-N-benzyl)cyclohexanols, in an Asymmetric Radical Cyclization, Atsushi Nishida, Fumie Shirato, and Masako Nakagawa, Tetrahedron Asymmetry, 2000, 11 (18), 3789-3805.

since 2010-10-07 / copyright @ 2010 薬品合成化学研究室. All Rights Reserved.