海洋生物（ホヤ、海綿、および微細藻類等）由来の生物活性天然物の探索等 Marine natural products
92. "Topsentinols A ~ J, New Sterols with Highly Branched Side
Chains from Marine Sponge Topsentia sp."
Ishibashi, M.; Yamagishi, E.; Kobayashi, J. Chem. Pharm. Bull.
1997, 45, 1435-1438.
91. "Studies on the
Macrolides from Marine Dinoflagellate Amphidinium sp.: Structures of Amphidinolides
R and S and a Succinate Feeding Experiment"
Ishibashi, M.; Takahashi, M.; Kobayashi, J. Tetrahedron
1997, 53, 7827-7832.
90. "Luteophanol A, New Polyhydroxyl
Compound from Symbiotic Marine Dinoflagellate Amphidinium sp."
Doi, Y.; Ishibashi, M.; Nakamichi, H.; Kosaka, T.;
Ishikawa, T.; Kobayashi, J. J. Org. Chem. 1997, 62,
3820-3823.
89. "Taurospongin A, Novel Acetylenic
Fatty Acid Derivative Inhibiting DNA Polymerase β and HIV Reverse Transcriptase
from Sponge Hippospongia sp."
Ishiyama, H.; Ishibashi, M.;
Ogawa, A.; Yoshida, S.; Kobayashi, J. J. Org. Chem. 1997, 62,
3831-3836.
88. "Absolute
Stereochemistry of Penaresidins A and B"
Kobayashi, J.; Tsuda, M.; Cheng, J.-F.; Ishibashi, M.; Takikawa, H.;
Mori, K. Tetrahedron Lett. 1996,
37, 6775-6776.
87. "Studies on the
Stereochemistry of Amphidinolides: Synthesis of a Diastereomer of the C-1 ~ C-9 Fragment of Amphidinolide C"
Ishiyama, H.; Ishibashi, M.; Kobayashi, J. Chem. Pharm. Bull.
1996, 44, 1819-1822.
86. "The Mode of
Rabbit Platelet Shape Change and Aggregation Induced by Theonezolide-A,
a Novel Polyketide Macrolide, Isolated from the
Okinawan Marine Sponge Theonella sp."
Rho,
M.-C.; Park, Y.-H.; Sasaki, S.; Ishibashi, M.; Kondo,
K.; Kobayashi, J.; Ohizumi, Y. Can. J. Physiol. Pharmacol. 1996, 74, 193-199.
85. "Total Synthesis
of Pseudodistomin C, a Sphingosine-Related
Piperidine Alkaloid from Tunicate Pseudodistoma
kanoko"
Doi, Y.; Ishibashi, M.;
Kobayashi, J. Tetrahedron 1996, 52, 4573-4580.
84. "Amphidinolide Q, a Novel 12-Membered Macrolide from the
Cultured Marine Dinoflagellate Amphidinium
sp."
Kobayashi, J.; Takahashi, M.; Ishibashi,
M. Tetrahedron Lett. 1996, 37,
1449-1450.
83. "Pseudodistomin C, a New Piperidine
Alkaloid with Unusual Absolute Configuration from the Okinawan Tunicate Pseudodistoma kanoko"
Kobayashi,
J.; Naitoh, K.; Doi, Y.; Deki, K.; Ishibashi, M. J.
Org. Chem. 1995, 60, 6941-6945.
82. "Amphidinolides O and P, Novel 15-Membered Macrolides from
the Dinoflagellate Amphidinium
sp.: Analysis of the Relative Stereochemistry and Stable Solution
Conformation"
Ishibashi, M.; Takahashi, M.; Kobayashi, J. J. Org.
Chem. 1995, 60, 6062-6066.
81. "Biosynthetic
Studies of Amphidinolide J: Explanation of the
Generation of the Unusual Odd-Numbered Macrocyclic
Lactone"
Kobayashi, J.; Takahashi, M.; Ishibashi,
M. J. Chem. Soc., Chem. Commun. 1995,
1639-1640.
80. "Three New Oxylipins Related to 3,6-Dioxo-4-docosenoic
Acid from Okinawan Marine Sponges, Plakortis
spp."
Takeuchi,
S.; Kikuchi, T.; Tsukamoto, S.; Ishibashi, M.;
Kobayashi, J. Tetrahedron 1995, 51, 5979-5986.
79. "Isolation of
Apo-9'-Fucoxanthinone from the Cultured Marine Dinoflagellate
Amphidinium sp."
Doi, Y.; Ishibashi, M.; Yamaguchi, N.; Kobayashi, J. J. Nat.
Prod. 1995, 58, 1097-1099.
78. "Revised Structure
of Pseudodistomin A, a Piperidine
Alkaloid Isolated from the Okinawan Tunicate Pseudodistoma
kanoko"
Ishibashi, M.; Deki, K.; Kobayashi, J. J. Nat. Prod. 1995,
58, 804-806.
77. "New
Bromine-Containing Unsaturated Fatty Acid Derivatives from the Okinawan Marine
Sponge Xestospongia sp."
Li,
Y.; Ishibashi, M.; Sasaki, T.; Kobayashi, J. J.
Chem. Research (S) 1995, 126-127; J. Chem. Research (M) 1995,
0901-0923.
76. "4,6-Dibromo-3-hydroxycarbazole
of Analogue of Caffeine-Like Ca2+ Releaser, a Novel Type of
Inhibitors of Ca2+-Induced Ca2+ Release in Skeletal
Muscle Sarcoplasmic Reticulum"
Takahashi, Y.; Furukawa, K.-I.; Kozutsumi,
D.; Ishibashi, M.; Kobayashi, J.; Ohizumi,
Y. Br. J. Pharmacol. 1995, 114,
941-948.
75. "Structure-Activity
Relationship of Bromoeudistomin D, a Powerful Ca2+
Releaser in Skeletal Muscle Sarcoplasmic Reticulum"
Takahashi,
Y.; Furukawa, K.-I.; Ishibashi, M.; Kozutsumi, D.; Ishiyama, H.;
Kobayashi, J.; Ohizumi, Y. Eur. J. Pharmacol. 1995, 288, 285-293.
74. "Absolute
Stereochemistry of Amphidinolide B"
Ishibashi, M.; Ishiyama, H.; Kobayashi, J. Tetrahedron Lett. 1994, 35, 8241-8242.
73. "Convolutamides A ~ F, Novel γ-Lactam Alkaloids from the
Marine Bryozoan Amathia convoluta"
Zhang,
H.-P.; Shigemori, H.; Ishibashi,
M.; Kosaka, T.; Pettit, G. R.; Kamano,
Y.; Kobayashi, J. Tetrahedron 1994, 50, 10201-10206.
72. "Amphidinin A, a Novel Amphidinolide-Related
Metabolite from the Cultured Marine Dinoflagellate Amphidinium sp."
Kobayashi, J.; Yamaguchi, N.; Ishibashi,
M. Tetrahedron Lett. 1994, 35,
7049-7050.
71. "Isolation and
Structure of Shimofuridins B ~ G from the Okinawan
Marine Tunicate Aplidium multiplicatum "
Doi, Y.; Ishibashi, M.;
Kobayashi, J. Tetrahedron 1994, 50, 8651-8656.
70. "Isolation and
Structures of Theonezolides B and C from the Okinawan
Marine Sponge Theonella sp."
Kondo,
K.; Ishibashi, M.; Kobayashi, J. Tetrahedron 1994,
50, 8355-8362.
69. "Amphidinolide N, a Novel 26-Membered Macrolide with
Remarkably Potent Cytotoxicity from the Cultured Marine Dinoflagellate
Amphidinium sp."
Ishibashi, M.;
Yamaguchi, N.; Sasaki, T.; Kobayashi, J. J. Chem. Soc., Chem. Commun. 1994, 1455-1456.
68. "Amphidinolide M, a Novel 29-Membered Macrolide from the
Cultured Marine Dinoflagellate Amphidinium
sp."
Kobayashi,
J.; Yamaguchi, N.; Ishibashi, M. J. Org. Chem.
1994, 59, 4698-4700.
67. "Nepheliosyne A, New C47 Acetylenic
Acid from the Okinawan Marine Sponge Xestospongia
sp."
Kobayashi, J.; Naitoh, K.; Ishida, K.; Shigemori, H.; Ishibashi, M. J.
Nat. Prod. 1994, 57, 1300-1303.
66. "Two New
Tryptophan-Derived Alkaloids from the Okinawan Marine Sponge Aplysina sp."
Kondo, K.; Nishi, J.; Ishibashi, M.;
Kobayashi, J. J. Nat. Prod. 1994, 57,
1008-1011.
65. "Plakoridine A, a New Tyramine-Containing
Pyrrolidine Alkaloid from the Okinawan Marine Sponge Plakortis sp."
Takeuchi,
S.; Ishibashi, M.; Kobayashi, J. J. Org. Chem.
1994, 59, 3712-3713.
64. "Stereochemistry
of the Modified Tryptophan Residues Contained in Konbamide
and Keramamide A Isolated from Marine Sponges of the
Genus Theonella"
Ishibashi, M.;
Li, Y.; Sato, M.; Kobayashi, J. Nat. Prod. Lett. 1994, 4,
293-296.
63. "Shimofuridin A, a Nucleoside Derivative Embracing an Acylfucopyranoside Unit Isolated from the Okinawan Marine
Tunicate Aplidium multiplicatum"
Kobayashi,
J.; Doi, Y.; Ishibashi, M. J.
Org. Chem. 1994, 59, 255-257.
62. "Amphidinolide K, a New 19-Membered Macrolide from the
Cultured Symbiotic Dinoflagellate Amphidinium
sp."
Ishibashi, M.; Sato, M.; Kobayashi, J. J. Org. Chem.
1993, 58, 6928-6929.
61. "The
Stereochemistry of Variabilin, an Antimicrobial Sesterterpene Isolated from Marine Sponges"
Ishibashi, M.;
Kurosaki, M.; Mikami, Y.; Kobayashi, J. Nat. Prod.
Lett.
1993, 3, 189-192.
60. "Two New
Polycyclic Aromatic Alkaloids from the Okinawan Marine Sponge Biemna sp."
Zeng, C.-M.; Ishibashi, M.;
Matsumoto, K.; Nakaike, S.; Kobayashi, J. Tetrahedron
1993, 49, 8337-8342.
59. "New Sesterterpenes with NGF Synthesis-Stimulating Activity from
the Okinawan Marine Sponge Hyrtios sp."
Doi, Y.; Shigemori, H.; Ishibashi, M.; Mizobe, F.;
Kawashima, A.; Nakaike, S.; Kobayashi, J. Chem.
Pharm. Bull. 1993, 41, 2190-2191.
58. "Biemnasterol, a New Cytotoxic Sterol with the Rare 22,25-Diene Side Chain Isolated from Marine Sponge Biemna sp."
Zeng, C.-M.; Ishibashi, M.; Kobayashi, J. J. Nat. Prod. 1993,
56, 2016-2018.
57. "Keruffaride: Structure Revision and Isolation from Plural
Genera of Okinawan Marine Sponges"
Ishibashi, M.; Zeng, C.-M.; Kobayashi, J. J. Nat. Prod. 1993,
56, 1856-1860.
56. "Manzamenones G and H, New Dimeric
Fatty-Acid Derivatives from the Okinawan Marine Sponge Plakortis
sp."
Kobayashi,
J.; Tsukamoto, S.; Takeuchi, S.; Ishibashi, M. Tetrahedron
1993, 49, 5955-5960.
55. "Theonezolide A, a Novel Polyketide
Natural Product from the Okinawan Marine Sponge Theonella
sp."
Kobayashi,
J.; Kondo, K.; Ishibashi, M.; Wälchli,
M. R.; Nakamura, T. J. Am. Chem. Soc. 1993, 115,
6661-6665.
54. "Untenone A, a New Cyclopentenone
from the Okinawan Marine Sponge Plakortis sp.
Corresponding to the Dienophile in the Biosynthesis
of Manzamenones"
Ishibashi, M.;
Takeuchi, S.; Kobayashi, J. Tetrahedron Lett.
1993, 34, 3749-3750.
53. "Amphidinolide J: a Cytotoxic Macrolide from the Marine Dinoflagellate Amphidinium
sp. Determination of the Absolute
Stereochemistry"
Kobayashi,
J.; Sato, M.; Ishibashi, M. J. Org. Chem. 1993,
58, 2645-2646.
52. Inhibition of
Topoisomerase I by Xestoquinone and Halenaquinone",
Bae, M.-A.;
Tsuji, T.; Kondo, K.; Hirase, T.; Ishibashi,
M.; Shigemori, H.; Kobayashi, J. Biosci.
Biotec.
Biochem. 1993, 57, 330-331.
51. "Keruffaride, a New All-Cis Cyclopentanepentol-Containing Metabolite from the Okinawan
Marine Sponge Luffariella sp."
Kobayashi, J.; Zeng, C.-M.; Ishibashi, M. J. Chem. Soc., Chem. Commun.
1993, 79-81.
50. "Luffariolides F and G, New Manoalide
Congeners from the Okinawan Marine Sponge Luffariella
sp."
Kobayashi, J.; Zeng, C.-M.; Ishibashi, M.; Sasaki, T. J. Nat. Prod. 1993,
56, 436-439.
49. "The Producer and
Biological Activities of SO-75R1, a New Mutactimycin
Group Antibiotic"
Maeda, A.; Yazawa, K.; Mikami, Y.; Ishibashi, M.;
Kobayashi, J. J. Antibiot. 1992,
45, 1848-1852.
48. "Pseudodistomin B: Revised Structure and First Total
Synthesis"
Kiguchi, T.; Yuumoto, Y.; Ninomiya, I.; Naito,
T.; Deki, K.; Ishibashi,
M.; Kobayashi, J. Tetrahedron Lett. 1992,
33, 7389-7390.
47. "Theoneberine: the First Brominated Benzyltetrahydroprotoberberine
Alkaloid from the Okinawan Marine Sponge Theonella
sp."
Kobayashi,
J.; Kondo, K.; Shigemori, H.; Ishibashi,
M.; Sasaki, T.; Mikami, Y. J. Org. Chem. 1992,
57, 6680-6682.
46. "Aplysidine, a New Nucleoside from the Okinawan Marine
Sponge Aplysina sp."
Kondo,
K.; Shigemori, H.; Ishibashi,
M.; Kobayashi, J. Tetrahedron 1992, 48, 7145-7148.
45. "Keramamide F, a New Thiazole-Containing
Peptide from the Okinawan Marine Sponge Theonella
sp."
Itagaki, F.; Shigemori, H.; Ishibashi, M.; Nakamura, T.; Sasaki, T.; Kobayashi, J.
J. Org. Chem. 1992, 57, 5540-5542.
44. "Manzamenones A ~ F from the Okinawan Marine Sponges Plakortis sp.: Novel Dimeric
Fatty Acid-Derivatives Possessing a Bicyclo[4.3.0]nonane Skeleton"
Tsukamoto,
S.; Takeuchi, S.; Ishibashi, M.; Kobayashi, J. J.
Org. Chem. 1992, 57, 5255-5260.
43. "Purealidins E ~ G, New Bromotyrosine
Alkaloids from the Okinawan Marine Sponge Psammaplysilla
purea"
Tsuda, M.; Shigemori, H.; Ishibashi, M.; Kobayashi,
J. J. Nat. Prod. 1992, 55, 1325-1327.
42. "Plakotenin, a New Cytotoxic Carboxylic Acid from the
Okinawan Sponge Plakortis sp."
Kobayashi, J.; Takeuchi, S.; Ishibashi,
M.; Shigemori, H.; Sasaki, T. Tetrahedron Lett. 1992, 33, 2579-2580.
41. "Luffariolides A ~ E, New Antileukemic
Sesterterpenes from the Okinawan Marine Sponge Luffariella sp."
Tsuda, M.; Shigemori, H.; Ishibashi, M.; Sasaki, T.; Kobayashi, J. J. Org. Chem.
1992, 57, 3503-3507.
40. "New Pentacyclic Compounds from the Okinawan Marine Sponge Xestospongia sapra"
Kobayashi, J.; Hirase, T.; Shigemori, H.; Ishibashi, M.; Myung-Ae, B.; Tsuji, T.; Sasaki, T. J. Nat. Prod.
1992, 55, 994-998.
39. "Purealidin D, a New Pyridine Alkaloid from the Okinawan
Marine Sponge Psammaplysilla purea"
Tsuda, M.; Shigemori, H.; Ishibashi, M.;
Kobayashi, J. Tetrahedron Lett. 1992,
33, 2597-2598.
38. "Niphatesine E ~ H, New Pyridine Alkaloids from the Okinawan
Marine Sponge Niphates sp."
Kobayashi,
J.; Zeng, C.-M.; Ishibashi,
M.; Shigemori, H.; Sasaki, T.; Mikami,
Y. J. Chem. Soc., Perkin Trans. 1 1992, 1291-1294.
37. "Ircinals A and B from the Okinawan Marine Sponge Ircinia sp.: Plausible Biogenetic Precursors of Manzamine Alkaloids"
Kondo,
K.; Shigemori, H.; Kikuchi, Y.; Ishibashi,
M.; Sasaki, T.; Kobayashi, J. J. Org. Chem. 1992, 57,
2480-2483.
36. "Agelasine G, a New Antileukemic
Alkaloid from the Okinawan Marine Sponge Agelas
sp."
Ishida, K.; Ishibashi, M.; Shigemori, H.; Sasaki, T.; Kobayashi, J. Chem. Pharm.
Bull. 1992, 40, 766-767.
35. "SO-75R1, a New Mutactimycin Derivative Produced by Nocardia
brasiliensis"
Mikami, Y.; Yazawa, K.; Ohashi, S.; Maeda, A.; Akao, M.; Ishibashi, M.; Kobayashi, J.; Yamazaki, C. J. Antibiot. 1992, 45, 995-997.
34. "1-(α-Diazobenzyl)pyrene:
a Reagent for Photolabile and Fluorescent Protection
of Carboxyl Groups of Amino Acids and Peptides"
Iwamura,
M.; Hodota, C.; Ishibashi,
M. Synlett 1991, 1, 35-36.
33. "Keramamides B ~ D, Novel Peptides from the Okinawan Marine
Sponge Theonella sp."
Kobayashi,
J.; Itagaki, F.; Shigemori,
H.; Ishibashi, M.; Takahashi, K.; Ogura, M.; Nagasawa, S.; Nakamura, T.; Hirota,
H.; Ohta, T.; Nozoe, S. J.
Am. Chem. Soc. 1991, 113, 7812-7813.
32. "New Congeners of Swinholides from the Okinawan Marine Sponge Theonella sp."
Tsukamoto,
S.; Ishibashi, M.; Sasaki, T.; Kobayashi, J. J.
Chem. Soc., Perkin Trans. 1 1991, 3185-3188.
31. "New Congeners of bistheonellides from Okinawan Marine Sponges of the Genus Theonella"
Kobayashi,
J.; Tsukamoto, S.; Tanabe, A.; Sasaki, T.; Ishibashi,
M. J. Chem. Soc., Perkin Trans. 1 1991, 2379-2383.
30. "Purealidins B and C, New Bromotyrosine
Alkaloids from the Okinawan Marine Sponge Psammaplysilla
purea"
Kobayashi,
J.; Tsuda, M.; Agemi, K.; Shigemori, H.; Ishibashi, M.;
Sasaki, T.; Mikami, Y. Tetrahedron 1991,
47, 6617-6622.
29. "Cystodytins D ~ I, New Tetracyclic Aromatic Alkaloids with
Potent Antineoplastic Activity from the Okinawan Marine Tunicate Cystodytes dellechiajei"
Kobayashi, J.; Tsuda, M.; Tanabe, A.; Ishibashi, M.; Cheng, J.-F.; Yamamura, S.; Sasaki, T. J.
Nat. Prod. 1991, 54, 1634-1638.
28. "Eudistomidins E and F, New β-carboline
Alkaloids from the Okinawan Marine Tunicate Eudistoma
glaucus"
Murata,
O.; Shigemori, H.; Ishibashi,
M.; Sugama, K.; Hayashi, K.; Kobayashi, J. Tetrahedron
Lett. 1991, 32, 3539-3542.
27. "Konbamide, a Novel Peptide with Calmodulin
Antagonistic Activity from the Okinawan Marine Sponge Theonella
sp."
Kobayashi,
J.; Sato, M.; Murayama, T.; Ishibashi, M.; Wälchli, M. R.;
Kanai, M.; Shoji, J.; Ohizumi, Y. J. Chem. Soc.,
Chem. Commun. 1991, 1050-1052.
26. "1H and
13C NMR Spectral Investigation on Amphidnolide
A, an Antileukemic Marine Macrolide"
Kobayashi, J.; Ishibashi, M.; Hirota, H. J. Nat. Prod. 1991, 54,
1435-1439.
25. "Keramamide A, a Novel Peptide from the Okinawan Marine
Sponge Theonella sp."
Kobayashi,
J.; Sato, M.; Ishibashi, M.; Shigemori,
H.; Nakamura, T.; Ohizumi, Y. J. Chem. Soc.,
Perkin Trans. 1 1991, 2609-2611.
24. "Amphidinolides G and H: New Potent Cytotoxic Macrolides
from the Cultured Symbiotic Dinoflagellate Amphidinium sp."
Kobayashi,
J.; Shigemori, H.; Ishibashi,
M.; Yamasu, T.; Hirota, H.;
Sasaki, T. J. Org. Chem. 1991, 56, 5221-5224.
23. "Manzacidins A-C, Novel Bromopyrrole
Alkaloids from the Okinawan Marine Sponge Hymenicacidon
sp."
Kobayashi,
J.; Kanda, F.; Ishibashi, M.; Shigemori,
H. J. Org. Chem. 1991, 56, 4574-4576.
22. "Amphidinolide F, a New Antineoplastic Macrolide from the Symbiotic
Marine Dinoflagellate Amphidinium
sp."
Kobayashi, J.; Tsuda, M.; Ishibashi, M.; Shigemori, H.; Yamasu, T.; Hirota, H.; Sasaki,
T. J. Antibiot. 1991, 44,
1259-1261.
21. "Revised
Structures of Prianosins C and D, Antineoplastic
Alkaloids from the Okinawan Marine Sponge Prianos
melanos"
Kobayashi, J.; Cheng, J.-F.; Yamamura, S.; Ishibashi,
M. Tetrahedron Lett. 1991, 32,
1227-1228.
20. "Penaresidins A and B, Two Novel Azetidine
Alkaloids with Potent Actomyosin ATPase Activating
Activity from the Okinawan Marine Sponge Penares
sp."
Kobayashi,
J.; Cheng, J.-F.; Ishibashi, M.; Wälchli,
M. R.; Yamamura, S.; Ohizumi, Y. J. Chem. Soc.,
Perkin Trans. 1 1991, 1135-1137.
19. "Iejimalides C and D, New Antineoplastic 24-Membered
Macrolide Sulfate from the Okinawan Marine Tuniate Eudistoma cf. rigida"
Kikuchi, Y.; Ishibashi, M.; Sasaki, T.;
Kobayashi, J. Tetrahedron Lett. 1991,
32, 797-798.
18. "Stelliferins A-F, New Antineoplastic Isomalabaricane
Triterpenes from the Okinawan Marine Sponge Jaspis stellifera"
Tsuda, M.; Ishibashi, M.; Agemi, K.; Sasaki, T.; Kobayashi, J. Tetrahedron 1991,
47, 2181-2194.
17. "Purealidin A, a New Cytotoxic Bromotyrosine-derived
alkaloid from the Okinawan Marine Sponge Psammaplysilla
purea"
Ishibashi, M.; Tsuda, M.; Ohizumi, Y.; Sasaki, T.; Kobayashi, J. Experientia
1991, 47, 299-300.
16. "9-Methyl-7-bromoeudistomin
D, a Powerful Radio-Labelable Ca++
Releaser Having Caffeine-Like Properties, Acts on Ca++-Induced
Ca++ Release Channels of Sarcoplasmic
Reticulum"
Seino,
A.; Kobayashi, M.; Kobayashi, J.; Fang, Y.-I.; Ishibashi,
M.; Nakamura, H.; Momose, K.; Ohizumi,
Y. J. Pharmacol. Exp. Ther.
1991, 256, 861-867.
15. "Niphatesines A ~ D, New Antineoplastic Pyridine Alkaloids
from the Okinawan Marine Sponge Niphates
sp."
Kobayashi,
J.; Murayama, T.; Kosuge, S.; Kanda, F.; Ishibashi, M.; Kobayashi, H.; Ohizumi,
Y.; Ohta, T.; Nozoe, S.;
Sasaki, T. J. Chem. Soc., Perkin Trans. 1 1990, 3301-3303.
14. "Hyrtiosins A and B, New Indole
Alkaloids from the Okinawan Marine Sponge Hyrtios
erecta"
Kobayashi,
J.; Murayama, T.; Ishibashi, M.; Kosuge,
S.; Takamatsu, M.; Ohizumi, Y.; Kobayashi, H.; Ohta, T.; Nozoe, S.; Sasaki, T. Tetrahedron
1990, 46, 7699-7702.
13. "Rigidin, a Novel Alkaloid with Calmodulin
Antagonistic Activity from the Okinawan Tunicate Eudistoma
cf. rigida"
Kobayashi,
J.; Cheng, J.-F.; Kikuchi, Y.; Ishibashi, M.;
Yamamura, S.; Ohizumi, Y.; Ohta,
T.; Nozoe, S. Tetrahedron Lett.
1990, 31, 4617-4620.
12. "Ageliferins, Potent Actomyosin
ATPase Activators from the Okinawan Marine Sponge Agelas
sp."
Kobayashi,
J.; Tsuda, M.; Murayama, T.; Nakamura, H.; Ohizumi, Y.; Ishibashi, M.;
Iwamura, M.; Ohta, T.; Nozoe,
S. Tetrahedron 1990, 46, 5579-5586.
11. "Amphidinolide E, a Novel Antileukemic
19-Membered Macrolide from the Cultured Symbiotic Dinoflagellate
Amphidinium sp."
Kobayashi,
J.; Ishibashi, M.; Murayama, T.; Takamatsu, M.;
Iwamura, M.; Ohizumi, Y.; Sasaki, T. J. Org. Chem.
1990, 55, 3421-3423.
10. "Cytotoxic
Macrolide from a Cultured Marine Dinoflagellate of
the Genus Amphidinium"
Kobayashi,
J.; Ishibashi, M.; Nakamura, H.; Ohizumi,
Y.; Yamasu, T.; Hirata, Y.; Sasaki, T.; Ohta, T.; Nozoe, S. J. Nat.
Prod. 1989, 52, 1036-1041.
9. "9-Methyl-7-bromoeudistomin
D, a Potent Inducer of Calcium Release from Sarcoplasmic Reticulum of Skeletal
Muscle"
Kobayashi,
J.; Ishibashi, M.; Nagai, U.; Ohizumi,
Y. Experientia 1989, 45,
782-783.
8. "Hymenosulfate, a Novel Sterol Sulfate with Ca-Releasing Activity from the Cultured Marine Haptophyte Hymenomonas
sp."
Kobayashi,
J.; Ishibashi, M.; Nakamura, H.; Ohizumi,
Y.; Hirata, Y. J. Chem. Soc., Perkin Trans. 1 1989, 101-103.
7. "Symbioramide, a Novel Ca2+-ATPase Activator from
the Cultured Dinoflagellate Symbiodinium
sp."
Kobayashi,
J.; Ishibashi, M.; Nakamura, H.; Hirata, Y.; Yamasu, T.; Sasaki, T.; Ohizumi,
Y. Experientia 1988, 44,
800-802.
6. "Metachromins A and B, Novel Antineoplastic Sesquiterpenoids from the Okinawan Sponge Hippospongia cf. metachromia"
Ishibashi, M.; Ohizumi, Y.;
Cheng, J.-F.; Nakamura, H.; Hirata, Y.; Sasaki, T.; Kobayashi, J. J. Org.
Chem. 1988, 53, 2855-2858.
5. "Amphidinolide C: The First 25-Membered Macrocyclic
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