Chemistry Enabling Biomolecule Transformations
Organic chemistry has been developed mainly for the purpose of producing desired molecules in test tubes. Although there are still many challenges to be solved, advanced chemical transformations are possible when targeting small molecules. However, when targeting peptides, proteins, or even cells, synthetic organic chemistry is extremely immature.
The Yamatsugu Laboratory is developing new synthetic chemistry that enables flexible chemical transformation of biomolecules such as proteins. By discovering a new reactivity that functions under physiological conditions (i.e., in neutral water at 37 °C), which is the reaction field of biomolecules, we create methods to chemically modifying proteins, creating and understanding their functions. We particularly focus on designing unique molecules and finding their unique reactivities.
2023/09/19 New undergraduate students joined our team.
2023/05/30 A Joint Usage/Research Project with Dr. Kounosuke Oisaki at National Institute of Advanced Industrial Science and Technology (AIST) has been adopted.
2023/04/24 Website opened!
2023/04/01 YAMATSUGU group launched!
Since 2023-04-24 / Copyright @ 2023 Synthetic Organic Chemistry Lab, Graduate School of Pharmaceutical Sciences, Chiba University